Jonas Verhellen
Theoretical physicist with a PhD in neuroscience. Postdoc in protein-protein interactions. Into art, science, and innovation.
Currently: Copenhagen 🇩🇰
Previously: Oslo 🇳🇴, London 🇬🇧, Brussels 🇧🇪
- Reposted by Jonas VerhellenAre you curious to see what my team and I are up to? Check out our group website here: peptide-discovery.ethz.ch
- Reposted by Jonas VerhellenOur team is looking for a visual journalist to report, design and code stories with us. You'll be able to learn from our skilled colleagues. I joined this team in 2021 and have continued to learn ever since. It's definitely a great work environment. Learn more about it or apply here: bit.ly/4kG33L6
- Made it to @intconfchemstr.social.edu.nl.ap.brid.gy just in time for the Mike Lynch Award (after about 6 hours of public transport).
- #ICCS25 A Chemoinformatics Journey (in 17 parts) by Mike Lynch Awardee Val Gillet.
- #ICCS25 GENEOnet: Accurate Protein Binding Pocket Detection
- Reposted by Jonas VerhellenAcademic freedom in the United States has found itself periodically under siege, but the current attacks from the federal government raise a new level of alarm. nyer.cm/u405qvQ
- Reposted by Jonas Verhellen[This post could not be retrieved]
- Big news! I've received a DKK 2.97 million postdoc grant from the Lundbeck Foundation to kick off my independent research at the University of Copenhagen! lundbeckfonden.com/news/young-t... #neuroscience #postdoc #LundbeckFoundation #mentalhealth
- I was very happy to discover Copenhagen has a statue for @janhjensen.bsky.social! 🦉🦉🦉
- Reposted by Jonas VerhellenWould you present your next NeurIPS paper in Europe instead of traveling to San Diego (US) if this was an option? Søren Hauberg (DTU) and I would love to hear the answer through this poll: (1/6)
- Reposted by Jonas VerhellenLearn more about #NordicAIR at our new website: nordicpartnership.ai (3/3)
- Reposted by Jonas VerhellenIntroducing olmOCR, our open-source tool to extract clean plain text from PDFs! Built for scale, olmOCR handles many document types with high throughput. Run it on your own GPU for free—at over 3000 token/s, equivalent to $190 per million pages, or 1/32 the cost of GPT-4o!
- Reposted by Jonas VerhellenCome work with me! We are looking to bring on more top talent to our language modeling workstream at @ai2.bsky.social building the open ecosystem. We are hiring: * Research scientists * Senior research engineers * Post docs (Young investigators) * Pre docs job-boards.greenhouse.io/thealleninst...
- Happy Valentine's day! And for all of us who need some extra love today - especially the NIH folks - here's a happy oxytocin molecule! 💞🧪
- Reposted by Jonas Verhellen1 week left to apply for this fully funded #compchem PhD opportunity part of the EU Marie Curie Doctoral Network, “CATALOOP” 🗓 Deadline: 31/01/2025 📥 How to Apply: submit your application via the university portal shorturl.at/nHyAo
- Reposted by Jonas VerhellenNew preprint from my group: Enhancing Chemical Synthesis Planning: Automated Quantum Mechanics-Based Regioselectivity Prediction for C-H Activation with Directing Groups doi.org/10.26434/che... #compchem
- Reposted by Jonas VerhellenActive-learning ML approach for catalytic free-energy calculations by Liu et al.: An MLP “committee” and constrained MD refine data, capturing reaction pathways 10^6× faster than ab initio. Their scheme ensures robust coverage of transitions and near-DFT precision. pubs.acs.org/doi/10.1021/...
- Reposted by Jonas VerhellenPlease forward to good candidates jobportal.ku.dk/videnskabeli...
- I used to share this video on the other place every year at Christmas ... time for a new tradition. Happy holidays BlueSky! youtu.be/Etflv7R6NKA?...
- Reposted by Jonas VerhellenCome join us on an exciting joint PhD project on ML for protein function with @kailalab.bsky.social -- We are looking for a strong quantitative candidate with prior experience in ML. The position is based in Gothenburg and is fully funded for 5 years. www.chalmers.se/en/about-cha...
- 🔬 More #SciComm! 🔬 This week’s figure shows how severe mental disorders affect the entire body. 🧠 While these disorders are known for their impact on brain functioning (blue), patients are also disproportionately affected by physical diseases (red). Details 👇!
- Severe mental disorders, like schizophrenia and bipolar disorder, are linked to higher risks of diseases affecting organs across the body. For each disease cluster, I highlighted a representative organ and the 95% confidence interval mortality risk ratio compared to the general population.
- Cardiovascular diseases are one example. People with schizophrenia face a strikingly higher mortality risk compared to those without. This highlights the urgent need for integrated care that addresses both mental and physical health!
- Despite decades of research, people suffering from severe mental health disorders still face an average 10 to 15 year reduction in life expectancy. In part due to current medical limitations and in part due the severity of the comorbidities.
- 🔬 Hello, BlueSky! Time for some more #SciComm! 🔬 Last week’s (procrastination 🙈) figure illustrates the frequency spectrum of genetic risk factors for Schizophrenia: common variants (blue), protein truncating variants (red), and copy number variations (green). More 👇!
- Common variants are frequent in the population, typically contribute modestly to risk, and are found by screening large populations. An example gene with common variations in schizophrenia is C4A which potentially plays a role in synaptic pruning, a critical brain development process.
- Protein-truncating variants, depicted in red, are rare mutations that disrupt the function of genes by prematurely shortening proteins. One such example is SETD1A, a methyltransferase, where mutations can interfere with transcription regulation, significantly increasing schizophrenia risk.
- Lastly, copy number variations (CNVs), marked in green, involve larger segments of DNA that are either duplicated or deleted. As seen with NRXN1, a gene essential for synaptic connectivity. Deletions of NRXN1 are strongly associated with schizophrenia.
- 🔬 Hello, BlueSky! Time for some #SciComm! 🔬 This week’s figure illustrates the onset and progression of schizophrenia, integrating symptom intensity (blue line), environmental and genetic risk factors (red boxes), and key disease milestones (white boxes) as they unfold across age.
- ✅ Importantly, a window of opportunity (green zone) represents the crucial timeframe for early detection and intervention, which could reshape long-term outcomes.
- This Figure is based on Figures 1.a and 1.b in the review paper "Altering the Course of Schizophrenia: Progress and Perspectives": www.nature.com/articles/nrd...
- Reposted by Jonas VerhellenStill believe that at the core of every exceptional research group are researchers who are both bright and kind and who value teamwork. #chemsky
