Our new paper is out in Nature 🎉. We show that m1Ψ in mRNA vaccines doesn’t just quiet immunity, it also directly enhance translation by reshaping ribosome dynamics in a sequence-dependent way 🧬
Full paper :
rdcu.be/eY5gx
N1-Methylpseudouridine directly modulates translation dynamics
Nature - N1-Methylpseudouridine enhances the translation of synthetic mRNAs, independently of innate immunity.