Richard Leggett
Bioinformatics/Nanopore/Metagenomics person at the Earlham Institute. This is my (unofficial) work related account - I do inane non-work stuff elsewhere!
earlham.ac.uk/leggett-group
- Reposted by Richard LeggettI am pleased to share that my first postdoc paper from the @halllab.bsky.social is now on bioRxiv! 🎉 We used long-read #metagenomics to explore how the gut microbiome and #antimicrobialresistance landscape shift across advanced chronic #liverdisease (ACLD) www.biorxiv.org/content/10.6...
- Exciting day at London’s Science Museum for the #InnovationforGrowth meeting where we’re showing off AirSeq technology from @earlhaminst.bsky.social and @nhm.org Meeting organised by @ukri.org to highlight the importance of research and innovation for economic growth.
- Know metagenomics and could spare 2 mins? I'm applying for funding to build a visual repository for metagenomic classification data (not sequence data). To support the application, I have a short 2 minute survey and it would be a big help if you could fill it in: docs.google.com/forms/d/e/1F...
- Know metagenomics and could spare 2 mins? I'm applying for funding to build a visual repository for metagenomic classification data (not sequence data). To support the application, I have a short 2 minute survey and it would be a big help if you could fill it in: docs.google.com/forms/d/e/1F...
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- Hey @moderation.bsky.app I set up a new account @martisoftware.bsky.social to give updates on a piece of open source scientific software and you've flagged it as spam because I followed 9 people and made 1 post. You've then failed to respond to my appeal. What is going on?
- Our MARTi @nanoporetech.com paper is now out in @genomeresearch.bsky.social after several years of development (particularly Ned Peel and Sam Martin). We'd love to hear from users about how you're using it, or suggestions for new features. @earlhaminst.bsky.social genome.cshlp.org/content/earl...
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- Excellently led by Mia Berelson.
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- A few places remaining for EI's latest "Nanopore metagenomics: from sample to analysis" course, running 8-9 July 2025. Will hopefully be a good introduction to wet lab and bioinformatics, plus the opportunity to discuss your projects. @nanoporetech.com www.earlham.ac.uk/events/nanop...
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- It’s nice to be attending the first annual conference of the Centre for Microbial Interactions, to which I am affiliated. So many Norwich researchers are involved in this great initiative. Also amused to discover my new Spanish naming on the name badge! #cminorwich25 @norwichmicro.bsky.social
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- Reposted by Richard LeggettWe're really excited to be part of Norwich Science Festival next month! Thanks to our PhD intern @rapher97.bsky.social we're running a poster trail around Norwich city centre from 1-22 February and an interactive stand at The Forum on 21 February: norwichsciencefestival.co.uk/whats-on/mar...
- For a slightly more sober analysis of Nvidia's new Project Digits "super" personal computer, see this great article at @theregister.com www.theregister.com/2025/01/07/n...
- Reposted by Richard LeggettNew year, new assemblies! I'm excited to announce Autocycler, my new tool for consensus assembly of long-read bacterial genomes! It's the successor to Trycycler, designed to be faster and less reliant on user intervention. Check it out: github.com/rrwick/Autoc... (1/5)
- It certainly is! But there is even more to it than scientists and data centres! 😃 🧬🔬🥼
- Do get in contact with me, or even better, Simon Tyrrell (not of this platform) if you want to know more!
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- I would guess deposits at SRA are typically delayed 1-many years from start of work, so not so much the state of sequencing in 2024, but fascinating figure nonetheless!
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- Reposted by Richard LeggettAlign to AllTheBacteria with low RAM (1-2Gb) and quickly (seconds if just 1000s of hits, 15 mins for a gene present in all 2.4 million genomes) using @shenwei356.bsky.social Lexicmap. So you can basically BLAST AllTheBacteria locally - but need 3-4Tb disk for index www.biorxiv.org/content/10.1...
