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#JBiolChem: Age-dependent topoisomerase I depletion alters recruitment of rDNA silencing complexes by Power, Lindsey N. et al.
www.jbc.org/article/S002...
Age-dependent topoisomerase I depletion alters recruitment of rDNA silencing complexes
Genomic instability and loss of proteostasis are two of the primary Hallmarks of Aging.
Although these hallmarks are well-defined in the literature, the mechanisms that drive
genomic instability and l...