did:plc:nn5747cbc3ykfvpkuou3ldf4

• 
  did:plc:nn5747cbc3ykfvpkuou3ldf4 handle.invalid · Jul 15, 2025
  @sebastien-levesque.bsky.social and I review therapeutic genome editing for inherited blood disorders rdcu.be/ewcZ3. We cover CRISPR, patient journey, DNA repair, patient access, genotoxicity, hemoglobinopathies, delivery, bone marrow failure, coselection, immunodeficiency, and more.
  

  CRISPR-based therapeutic genome editing for inherited blood disorders

  Nature Reviews Drug Discovery - CRISPR-based technologies provide a diverse set of tools to correct pathogenic mutations. This Review describes the promise and the challenges of genome editing...

  rdcu.be
  1

  Repost Quote post

  View on BlueskyCopy Bluesky URLCopy post URLTranslate postShow all post labels
• 
  did:plc:nn5747cbc3ykfvpkuou3ldf4 handle.invalid · Jun 18, 2025
  Excited to share our latest where we describe a gene editing method termed prime assembly that enables RNA programmable targeted integration of gene-sized DNA sequences in nondividing cells without dsDNA or nuclease-driven DSBs. See thread by incomparable @Seb. Also complementary work Sontheimer/Xue
  • sebastien-levesque sebastien-levesque.bsky.social · Jun 17, 2025
    [Not loaded yet]
  Repost Quote post

  View on BlueskyCopy Bluesky URLCopy post URLTranslate postShow all post labels