PGC Functional Genomics
Functional Genomics working group of the Psychiatric Genetics Consortium.
pgc.unc.edu/for-researchers/wor…
- Reposted by PGC Functional GenomicsSo, who are the the Functional Genomics Working Group? 🎯Our goal is to understand how genes🧬, cells🦠and molecules💠contribute to psychiatric disorders🧠 We work with other PGC groups and different 'omics data (methylation, cytometry, single cell etc.) to do this🧪 🧵1/3
- Reposted by PGC Functional GenomicsThe @fg-pgc.bsky.social is all about understanding how our genetic findings🔬translate into psychiatric conditions 🧠 We have 5 project groups, and we are excited to introduce the✨Functional Validation✨group first! We asked them for a status update and a highlight of the year...
- Reposted by PGC Functional GenomicsThe second of our 5 project groups we are thrilled to introduce is the✨Isoforms✨group! Isoforms are different versions of RNA transcripts or proteins🧬 They are a result of splicing✂️during gene expression and are an important part of how one gene can act in different ways!
- Reposted by PGC Functional GenomicsNext up is the awesome✨Methylation-wide association studies✨group! AKA the MWAS group😉 #Epigenetics are changes that happen to DNA expression🧬without actually changing the sequence! Instead, these changes happen to molecules that are attached to the DNA - how cool 🤯!
- Reposted by PGC Functional GenomicsOur fourth group is the ✨Multi-level Quantitative Trait Loci✨group! 🧬AKA themQTL group🧬 🔎QTL analysis is a way to understand how genetic sequences🧬affect gene expression... 🧐Think RNA transcripts and proteins! All these methods to understand genetics🤩
- Reposted by PGC Functional GenomicsBefore we get started, let’s introduce our two Social Media Reps - @natashaberthold.bsky.social and @evacschulte.bsky.social! We're here for the #functionalgenomics🧬, and #Science #Communication📡is a🔑key part! 💫Check out their profiles💫
