POP-GEM Lab
Population #Genomics & Environment in #Mentalhealth | studying #psychiatricgenetics #behaviorgenetics | directed by Roseann Peterson| SUNY Downstate | VCU_VIPBG
pop-gem-lab.com
- New publication in @nature.com. MVP EHR linked genomics enables ancestrally diverse analyses, uncovering ancestry independent signals, 100 plus new schizophrenia loci, and convergent neurobiology with global relevance. www.nature.com/articles/s41... @timbigdeli.bsky.social @panosroussos.bsky.social
- New open-access Translational Psychiatry paper: multi-omic integration + drug repurposing to identify FDA-approved treatments for opioid use disorder. Led by POP-GEM’s B. Todd Webb, PhD. Approach generalizable across complex traits & disorders. www.nature.com/articles/s41... #OUD
- (1/2) Congrats to Tadeusz Wroblewski and co-authors on their new JAMA Network Open paper using NIH All of Us data! The study reveals racial disparities in post-TBI neuropsychiatric outcomes and highlights the impact of structural and social factors on recovery. @timbigdeli.bsky.social
- (2/2) Link here 🔗: jamanetwork.com/journals/jam...
- (1/6) We’re excited to present “Advancing the Understanding of Depression Genetics Through Research on Latin American Genomes” at #WCPG2025! 🌎✨ Mon Oct 20 | 9:45–11:15 AM Blue River 3 – Convention Center, Cancún Led by Drs. @roseannpeterson.bsky.social @nscorralfrias.bsky.social 🧵...
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- (6/6) Dr. @nscorralfrias.bsky.social will discuss the LAGC-MDD’s meta-analytic GWAS efforts, followed by Dr. @roseannpeterson.bsky.social remarks on the importance of including ancestrally diverse populations in psychiatric genomics. #WCPG2025 #LAGC #PsychiatricGenomics
- (2/6) Latin America has one of the highest global rates of MDD (~12%) yet remains underrepresented in psychiatric genetics. This session explores new findings addressing that gap through cross-ancestry research. #WCPG2025 #LAGC
- Congratulations to #LanieMullins, PhD student #VCU_VIPBG, on receiving the Rising Star Award at #BGA2025 🎉 Her poster using #UKBiobank data linked immune system markers (MLR/NLR) to depression, with NLR emerging as a stronger predictor in older adults.
- 🚨 New paper out! In a collaboration across MVP, FinnGen & UK Biobank, we conducted a phenome-wide study of sex chromosome trisomies (SCT) in 1.5M participants. Findings reveal shared disease risks across SCT. 🔗 www.sciencedirect.com/science/arti...
- 🧬 Join us at #APA2025 in LA for the invited symposium: "Electronic health records, genetics, and the promise of precision psychiatry" Tues, May 20th | 3:45–5:15 PM PDT @roseannpeterson.bsky.social opens with PsycheMERGE: using EHR-linked biobanks to promote equity in psychiatric genomics.
- 🧠 Also in the invited symposium:"Electronic health records, genetics, and the promise of precision psychiatry" Tues, May 20th | 3:45–5:15 PM PDT Dr. Tim Bigdeli shares Million Veteran Program insights on EHRs, polygenic scores & dementia. #EHR #Genomics @timbigdeli.bsky.social
- (1/1) 🧠🌎 Just published in Nature Genetics: “Psychiatric genetics in the diverse landscape of Latin American populations” A comprehensive review of progress, challenges, and future directions. 🔗 www.nature.com/articles/s41... #PsychiatricGenetics #GlobalGenomics
- (2/2) Despite the high burden of mental health conditions, Latin American and Caribbean populations remain underrepresented in psychiatric GWAS. This review highlights: 🧬 Genetic diversity 📉 Gaps in data and representation 🤝 Opportunities for collaboration
- (3/3) To advance psychiatric genetics in Latin America & the Caribbean: 🧬 Inclusive GWAS 📊 Regional data & infrastructure 👏 Big thanks to the authors & LAGC! @egatkinson.bsky.social @giustilab.bsky.social @janitzamontalvo.bsky.social @roseannpeterson.bsky.social
- 🌟New review in Psychiatric Clinics: Closing diversity gaps in psychiatric genomics is vital for health equity. 📖Read: doi.org/10.1016/j.ps... @roseannpeterson.bsky.social @giustilab.bsky.social @janitzamontalvo.bsky.social @nokewole.bsky.social
- New preprint🌍 Our trans-ancestry GWAS in UK Biobank uncovers novel risk loci for major depression, improving genetic insights across populations. 🔗: www.medrxiv.org/content/10.1... @madhurbsingh.bsky.social @gentyae.bsky.social @pbb319.bsky.social timbigdeli.bsky.social @roseannpeterson.bsky.social
- New paper! Led by Kirsten J. M. van Hooijdonk & Jacqueline Vink, this study finds no bidirectional causal link between diet/physical activity & depression/anxiety using triangulation. No strong causal evidence! @zoereed.bsky.social @madhurbsingh.bsky.social 📖 doi.org/10.1017/S003...
- 🚀 New paper by @madhurbsingh.bsky.social on smoking & DNA methylation via twin-based MR using @ntrbiopsy.bsky.social data! Supervised by Mike Neale, @jennyvandongen.bsky.social, & Conor Dolan. Co-authors: @dlapato.bsky.social, @charlesbreeze.bsky.social. 🔗 doi.org/10.1007/s106...
- Thrilled to share some amazing news— @madhurbsingh.bsky.social, supervised by Roseann Peterson, PhD, and Michael C. Neale, PhD, has been awarded VCU VIPBG's Kenneth S. Kendler Award for Excellence in Predoctoral Research!
