Brad Weiler
Postdoc @miamirosenstiel.bsky.social and NOAA AOML Coral Program 🪸 | PhD from @delCampoLab | Coral Holobiont Function and Composition through Health and Disease 🔬🦠🧬
- New study by Rossin et al. visualizing SCTLD progression in multiple coral species 🪸 “The lysing of gastrodermal cells leads to separation of the gastrodermis from the mesoglea, and finally to liquifying necrosis.” Check it out here: www.nature.com/articles/s41...
- Reposted by Brad WeilerHeat-stressed #corals and the important role of picoplankton-derived nitrogen link.springer.com/article/10.1...
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- Reposted by Brad WeilerThe Microbiome Within a Microbe: Rethinking Blastocystis Biology onlinelibrary.wiley.com/doi/10.1111/... #protists #microbiome
- Reposted by Brad Weiler@michaeltconnelly.bsky.social et al. sequenced 342 Pocillopora coral samples from the Eastern Tropical Pacific, revealing four distinct species; algal symbiont community profiling identified dominant symbionts that varied according to host species. 🔗 doi.org/10.1093/gbe/evaf235 #genome #evolution
- Reposted by Brad WeilerLast postdoc pub finally out!! This one was a doozy, but really enjoyable to work on. Involved some creative problem solving in regards to analysis of transcriptomic data from complex experimental designs. In the end I learned A LOT from this team and think the final product is pretty cool.
- Reposted by Brad Weiler#ProtistsOnSky no 'swimming' by 𝘝𝘢𝘮𝘱𝘺𝘳𝘦𝘭𝘭𝘢, definitively no 'staying still'. just a relaxed walk towards the lunch...
- Do microbes get more food by swimming or staying still? Turns out both work, and cilia help them pull in nutrients no matter the strategy. buff.ly/vK3GmK5
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- Reposted by Brad WeilerEls coralls dormen com nosaltres, però la seva simbiosi no descansa 🪸 📕 Un equip de recerca de l’ @ibe-barcelona.bsky.social ha descobert que els coralls descansen a la nit tot i no tenir sistema nerviós, mentre que els seus microorganismes continuen actius. 💤 👉shorturl.at/wC0eU
- Cool web story on our diel coral research! Check it out here: shorturl.at/qx9K6
- Corals sleep like us, but their symbiosis does not rest🪸 📕 A research team from the @ibe-barcelona.bsky.social has discovered that corals rest at night despite not having a nervous system, while their microbes remain active.🧵 #UnravellingEvolution 👉shorturl.at/qx9K6
- Reposted by Brad Weiler✅ For the first time, it has been observed in situ that "sleep" helps maintain the host-microbe balance in very primitive organisms, a mechanism that could be extremely ancient in animal evolution.
- Reposted by Brad Weiler🌙 When the sun sets, corals recover from the stress accumulated during the day, caused by the intense activity of their symbiotic microorganisms. 💤 #DiscoveringLife #ConservingBiodiversity 👉doi.org/10.1016/j.chom.2026…
- Reposted by Brad WeilerCorals sleep like us, but their symbiosis does not rest🪸 📕 A research team from the @ibe-barcelona.bsky.social has discovered that corals rest at night despite not having a nervous system, while their microbes remain active.🧵 #UnravellingEvolution 👉shorturl.at/qx9K6
- 🚨New Pub Alert🚨 We present a system-level molecular framework of natural diel regulation in the stony coral P. strigosa, integrating host & symbiodiniaceae transcriptomics with microbiome dynamics over 6hr intervals. Amazing to publish this PhD work @miamirosenstiel.bsky.social 👉 shorturl.at/TzYEr
- We uncover transcriptional rhythms in the coral, including dawn initiated RNA biosynthesis, midday & dusk regulation of phosphate metabolism, and midnight activation of stress and repair pathways. Breviolum sp. displays tightly regulated cell cycle dynamics and nutrient transport oscillations.
- To help reduce the annotation gap of functional assignment in non-model organisms like corals, we supplemented our host gene ontology enrichment terms using protT5 protein language model to predict functions for poorly annotated proteins, adding more context beyond standard homology-based pipelines.
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View full threadThis project was so fun thanks to @ambonacolta.bsky.social and @fonamental.bsky.social through the lack of sleep during those 6 hr interval dives over 3 days. Massive thank you to everyone involved, including CARMABI marine station in Curaçao, our collaborators, and @cp-cellhostmicrobe.bsky.social
- Reposted by Brad WeilerHappy to have contributed to the #protists section of this @ergabiodiv.bsky.social whitepaper 👉 From Permits to Samples: Addressing Key Challenges for High-Quality Reference Genome Generation in Europe onlinelibrary.wiley.com/doi/10.1111/...
- Reposted by Brad WeilerOCEAN LEADERS FELLOWSHIP: Applications now open (Sustainable Oceans Alliance) Learn more here: www.soalliance.org/ocean-leader... #coralreefs #fellowships #financialsupport #marineconservation #ocean #funding #marineecology #marinebiology #oceanleaders #sustainability
- A lot of great discussion at @univmiami.bsky.social IDSC Day 2026 about advances in AI & Machine Learning- including critical ethics issues. Presented our newest work adapting protein language models (PLMs) in corals to enhance functional annotations. Thanks for hosting such an awesome event IDSC!
- Thanks to all our collaborators and funders, with a special shoutout to the @univmiami.bsky.social Frost Institute for Data Science & Computing (IDSC) to making this all possible! @fonamental.bsky.social @ambonacolta.bsky.social
- Reposted by Brad WeilerEmergency sampling in the USVI as part of our NSF Diadema project. Didn’t even know I was coming down here yesterday at breakfast; today flew down, and was in the water within 45 mins of arrival. Unfortunately, it’s happening at our site (but this is good for our study). Urchins are dying…
- Reposted by Brad WeilerOut now in Environmental Microbiome! 🧬 By re-analyzing microbialite sequencing data, we show that chromerid algae (the closest photosynthetic relatives of apicomplexans) are consistent and widespread associates of microbialites across diverse marine and freshwater environments worldwide 🌎
- Reposted by Brad WeilerEmergency for Caribbean collaborators: There appears to be Diadema mortality somewhat reminiscent of the 2022 die off occurring right now in the USVI. If anyone hears of wider occurrences in the region please let us know! Please re-post!
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- Reposted by Brad WeilerWestern University is looking for a Canada Research Chair (CRC) Tier 1 in Metabolomics. We are intent on building capacity in this system and the ideal candidate will help build infrastructure and mentor junior faculty. Please see the job ad at: uwo.ca/facultyrelat...
- Reposted by Brad Weiler💾 any2fasta 0.8.1 is released! The FASTA format is now 40 years old (Pearson & Lipman) and any2fasta makes it easy for your scripts and pipelines that accept FASTA to also accept other formats, even if compressed! eg. .gbk.gz #bioinformatiocs #microbiology #genomcs github.com/tseemann/any...
- Reposted by Brad WeilerNew preprint out! Using ~75k environmental OTUs + 77 fossil calibrations, we reconstructed a Proterozoic timeline of eukaryote evolution. Our results show crown eukaryotes were already diversifying >1.6 Ga, long before the first undisputed fossils (~1.05 Ga). 🔗 DOI: www.biorxiv.org/content/10.6...
- Reposted by Brad WeilerStony Coral Tissue Loss Disease Results in Persistent Microbial-Level Disturbances on Coral Reef Ecosystems enviromicro-journals.onlinelibrary.wiley.com/doi/10.1111/... #corals #microbiome #holobiont
- Reposted by Brad Weiler🧪📍🌊 🦑🍎 Marine Scientist Position – Smithsonian Tropical Research Institute (STRI), full-time, permanent Marine Scientist position based in Panama. Application review begins February 15, 2026 (open until filled). Early-career researchers are strongly encouraged to apply. www.stri.si.edu
- Reposted by Brad WeilerExcited to share the final version of our study on Nematostella cell type regulatory programs. Part of our @erc.europa.eu StG project, this was a challenging 5-year effort extraodinarily led by @aelek.bsky.social and @martaig.bsky.social. www.nature.com/articles/s41...
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- Reposted by Brad WeilerSome parasites like it hot, some don’t www.pnas.org/doi/abs/10.1... #symbiosis
- Reposted by Brad WeilerLooking for a postdoc in 2026? The Ewel fellowship at UF provides $70K salary and $20K research support for 2 yrs. I'm happy to sponsor a postdoc interested in microbial ecology of Florida coastal ecosystems (seagrass, coral, mangroves, springs). 🦠 Due 1/11/26 postdoc.aa.ufl.edu/current-post...
- Reposted by Brad WeilerA new combtooth blenny genome just dropped! Assembled from recycled ONT data + HiC + RNAseq. Thanks, Nikita Kulikov, Kim Joffroy, @ambonacolta.bsky.social @delcampolab.bsky.social for your hard work
- Reposted by Brad WeilerSo happy this is finally out! We reconstructed the 1st large-scale spatiotemporal dataset of 600+ MAGs from San Francisco Bay and show they have functional redundancy in key N and S pathways. These functions may better recover from disturbance in this highly urban estuary 💧
- Reposted by Brad WeilerGlad I got to contribute a little bit to this study on the microbiomes of deep sea annelids! 🪱 🦠 🌊 Check out Grimes et al here: authors.elsevier.com/c/1mEmNI7ED3... #Microbiomes #WormWednesday
- Reposted by Brad WeilerInteresting new research on the transcriptomics of Symbiodinid thermal tolerance from Xiang et al
- Reposted by Brad WeilerNew preprint! We explore how gutless marine worms and their bacterial symbionts use organosulfur compounds like DMSP and DMS - key molecules in marine sulfur cycling. Our results show that these compounds support carbon and energy metabolism in the Olavius algarvensis symbiosis.
- Reposted by Brad WeilerOne more week to apply to this PhD position on working out an endosymbiosis relationship in a protist. Please share widely to prospective PhD student #protistsonsky
- We are looking for a PhD student to work on an exciting plastid endosymbiosis in microbial eukaryotes. This position involves sampling, exciting microscopy such as CARDFISH, ExM and FIBSEM, single-cell transcriptomics and more. #protistsonsky 1/2
- Reposted by Brad WeilerWork I co-led with @jnoms.bsky.social is now online at @cp-cellhostmicrobe.bsky.social ! We revealed a previously unrealized diversity of viral immune-evasion proteins that selectively destroy different cyclic nucleotide signals used in bacterial immunity. www.sciencedirect.com/science/arti...
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- Reposted by Brad Weiler📣 Open position: We are looking for a new #ScientificLead for the #SILVA database 🧬🖥️ You will be responsible for guiding the development of this important resource and for curating the SILVA taxonomy🌳and more! 👉 www.dsmz.de/dsmz/career/... Read and share ‼️ #sciencejobs 🦠🧪 #career #taxonomy
- Reposted by Brad Weiler1/ Bioinformaticians: our people skills matters as much as our code Here’s why communication is your most underrated tool 🧵
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- Reposted by Brad WeilerThe Lariviere lab at UMiami is recruiting PhD students! Incoming students will join us in studying host-microbe interactions in the honey bee gut, using molecular and genetic approaches. Please see the attached flyer for more details. #Symbiosis #SymbioSky #MicroSky #PhDOpportunity #AcademicJobs
- Reposted by Brad WeilerWe are looking for a PhD student to work on an exciting plastid endosymbiosis in microbial eukaryotes. This position involves sampling, exciting microscopy such as CARDFISH, ExM and FIBSEM, single-cell transcriptomics and more. #protistsonsky 1/2
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- Reposted by Brad WeilerLooking for a postdoctoral fellowship in 2026? The Ewel fellowship at UF provides salary and research support for 2 years. I would be happy to sponsor a postdoc interested in microbial ecology of Florida coastal ecosystems. postdoc.aa.ufl.edu/current-post...
- Reposted by Brad WeilerJob Opening **ASSISTANT PROFESSOR MARINE ECOLOGY**, Department of Biological Sciences, University of Rhode Island. jobs.uri.edu/postings/15960
- Reposted by Brad Weiler1. Postdoc in plant-fungal interactions: jobsite.sheffield.ac.uk/job/Research... 2. Postdoc in molecular plant-microbe interactions: jobsite.sheffield.ac.uk/job/Research... 3. Research technician: jobsite.sheffield.ac.uk/job/Technici... (Pls share!)
- Reposted by Brad WeilerOligonucleotide design meets big data: We present oligoN-design, a simple, reproducible and versatile open-source tool to design specific primers and probes directly from large environmental DNA datasets. 🔗 DOI: doi.org/10.1101/2025... 👉 github.com/MiguelMSandi...
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- Reposted by Brad WeilerDo you teach #rstats? Do your students complain about how lame and old-fashioned dplyr is? Don't worry: I have the solution for you: github.com/hadley/genzp.... genzplyr is dplyr, but bussin fr fr no cap.
- Reposted by Brad WeilerSo happy to share this! Bacteriocins were first discovered over 100 years ago, but what do they actually do? We look at >1000 bacteriocin plasmids and find links to virulence and antimicrobial resistance, and frequent bacteriocin sharing in Enterobacteriaceae. www.nature.com/articles/s41...
