Jonathan Wirsich
EEG-fMRI, multimodal connectomics
- Reposted by Jonathan WirsichNew PhD and post-doc job openings! Join me and Prof. Nina Kazanina @ Uni Geneva, Switzerland, to take part in an exciting project on relations and binding in language and vision, explored with cutting-edge neurophysiology (#iEEG and MEG). Full details in the job offer below.
- Reposted by Jonathan WirsichFor 15(!) years I’ve been teaching introductory #MRI to grad students, and struggled to find a textbook for a wide variety of backgrounds. I'm happy to share an online textbook I created, fully open source (including code for generating figures and plots shown): larsonlab.github.io/MRI-educatio...
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- Reposted by Jonathan WirsichThe best brain-machine interface remains the mouth. Evolution spent 4B years of evolution on R&D developing the device, so I guess it's not that surprising. Yet it still rarely appears as a baseline in evaluations of new devices.
- Reposted by Jonathan WirsichNature Sci Rep publishes incoherent AI slop. eLife publishes a paper which the reviewers didn't agree with, making all the comments and responses public with thoughtful commentary. One of these journals got delisted by Web of Science for quality concerns from not doing peer review. Guess which one?
- Reposted by Jonathan WirsichEvidence from 14 research funding programmes confirms that early winners tend to keep winning (Matthew effect). But the idea that an early setback makes you stronger later doesn’t replicate widely. buff.ly/UEtcRd4
- Check out our newest demonstrating feasabilty of sub-mm whole brain EEG-fMRI at 7T. Happy to have been part of this amazing collaboration and thank you so much to Cristina and João for leading this project 😊👍.
- New paper in Imaging Neuroscience by C. Sainz Martinez, J. Jorge, et al: An optimized framework for simultaneous EEG-fMRI at 7T enabling safe, high-quality human brain imaging with millisecond temporal resolution and sub-millimeter spatial resolution doi.org/10.1162/IMAG...
- Reposted by Jonathan WirsichIs the the neuroimaging community (broadly conceived) submitting to 𝗡𝗲𝘂𝗿𝗼𝗶𝗺𝗮𝗴𝗲 again????? Not to be publication police but the shift had seemed major 1-2 years ago. Looking at the editorial board it seems to have serious scientists once more. Curious about thoughts of the community.
- Reposted by Jonathan WirsichMonty Python understood p-hacking
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- Reposted by Jonathan WirsichGet ready for the biggest #ABIM yet! 🥳 We're celebrating our 20th anniversary with a special edition you won't want to miss. 🗓️ Registration & abstract submission: www.unige.ch/ABIM/partici... 💰Early bird fee ends November 9th! #ABIM2026 #neuroimaging
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- Reposted by Jonathan WirsichWhen @laurapritschet.bsky.social & Pavel Shapturenka set out to build the 28&Me + 28&He datasets, I don't think any of us could've predicted the spectacularly creative ways the datasets would be used years later. That's the power of open science. 👇🏼
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- Reposted by Jonathan WirsichNew layer-fMRI preprint using simultaneous layer-fMRI with EEG at 7T. Establishing an acquisition and analysis setup to capture layer-fMRI correlates of spontaneous alpha power variations. By Marsh et al. doi.org/10.1101/2025...
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- Reposted by Jonathan WirsichEver wondered if your interesting brain-behavior correlation was over- or under-estimated due to head motion, but were afraid to ask? We’ve created a motion impact score for detecting spurious brain-behavior associations, now available in Nature Communications! doi.org/10.1038/s414...
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- Reposted by Jonathan WirsichLaunched in 2023, Imaging Neuroscience is now firmly established, with full indexing (PubMed, etc.) and 700 papers to date. We're very happy to announce that we are able to reduce the APC to $1400. Huge thanks to all authors, reviewers, editorial team+board, and MIT Press.
- Reposted by Jonathan WirsichOur review discussing the potential use of laminar fMRI for probing the role of cortical layers in epileptic seizure propagation and spread as well as it possible future clinical applications out in Brain (well as accepted manuscript!) academic.oup.com/brain/advanc...
- Reposted by Jonathan WirsichHappy to see this out: our new preprint shows that laminar GE-BOLD fMRI decoding isn’t immune to vascular draining biases. Simulations reveal false positives due to multivariate signal spread across layers, but oversampling + deconvolution can (sometimes) improve specificity.
- Vascular draining confounds laminar decoding in fMRI biorxiv.org/content/10.1101/202…
- Reposted by Jonathan WirsichNew paper🥳 🧠 In TLE, brain changes go beyond the temporal lobe & beyond normal aging. Our ENIGMA study (769 patients, 18 sites) found widespread gray & white matter decline, especially after 55. By Judy Chen and a terrific intl' team Time for earlier diagnosis & deeper research bit.ly/3HRYeQt
- Interested in Epileptic Discharges? In need of a data set to validate your source reconstruction models based on clinical outcome? Check out our newest: www.nature.com/articles/s41... Big thanks to B. Vorderwülbecke, S. Vuillémoz et al. ! - @seeber.bsky.social @cibm.bsky.social
- Data available via @ebrains.bsky.social : doi.org/10.25493/B3B... Also big thanks to their contribution :)
- Reposted by Jonathan WirsichIn 2019, the CNeuroMod team and 6 participants began a massive data collection journey: twice-weekly MRI scans for most of 5 years. Data collection is now complete! 1/🧵
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- Reposted by Jonathan WirsichThanks to all (co)authors & reviewers for their contribution to this study on #layer specific changes in #sensory #cortex across the #lifespan in #humans & #mice now out in @natneuro.nature.com Here is a short summary of our findings 1/6
- 🧠 The human brain ages less than thought and in layers – at least in the area of the cortex responsible for the sense of touch. See study @natneuro.nature.com by @estherkuehn.bsky.social and colleagues at DZNE, @hih-tuebingen.bsky.social and @uni-magdeburg.de: 👉 www.nature.com/articles/s41...
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- Reposted by Jonathan WirsichToday, our article "The entities enabling scientific fraud at scale are large, resilient, and growing rapidly" is finally published in PNAS. I hope that it proves to be a wake-up-call for the whole scientific community. reeserichardson.blog/2025/08/04/a...
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- Reposted by Jonathan Wirsich1 To predict the behaviour of a primate, would you rather base your guess on a closely related species or one with a similar brain shape? We looked at brains & behaviours of 70 species, you’ll be surprised! 🧵Thread on our new preprint with @r3rt0.bsky.social , doi.org/10.1101/2025...
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- Reposted by Jonathan WirsichNew layer-fMRI preprint by Clauner et al. Interleaved EEG and layer-fMRI is used to investigate feature-specific and unspecific correlates of alpha and gamma oscillations in superficial and deeper layers. doi.org/10.1101/2024...
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- Reposted by Jonathan WirsichEvery machine in a Hospital that diagnoses your body without cutting you open is based on a principle of Physics, discovered by a Physicist who had no interest in Medicine. If you think the world doesn’t need Basic Science, or that somehow Science has failed you, think again.
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- Reposted by Jonathan WirsichOn this day 2y ago we announced our move away from the huge profits that NeuroImage makes for Elsevier. Things at Imaging Neuroscience have progressed fantastically thanks to the support for this move by the brain imaging community and @mitpress.bsky.social. 565 papers published already!
- Reposted by Jonathan WirsichFirst post on an exciting new manuscript online today @natneuro.nature.com - in collab with @lucinauddin.bsky.social and Catie Chang. We take a fresh look at the physiological dynamics associated with the global signal 🧠 ... www.nature.com/articles/s41... Read here: rdcu.be/ek01F
- Reposted by Jonathan WirsichGrowing evidence that careful experimental design of ADC-fMRI yields functional information distinct from BOLD prompts the question of residual vascular sources. We thus analyzed the ADC- and BOLD-fMRI responses to non-neuronal vascular fluctuations. 🥁 Led by I. de Riedmatten & A. Spencer #FIREPATH
- Evaluating the dependence of ADC-fMRI on haemodynamics inbreath-hold and resting-state conditions biorxiv.org/content/10.1101/202…
- Reposted by Jonathan WirsichThis new layer-fMRI manuscript combines layer-fMRI with the high temporal resolution of EEG. This study shows how laminar specific information arrives at different onset times. By Carricarte et al., doi.org/10.1101/2025...
- Reposted by Jonathan WirsichIMO one of the solution to the reproducibility crisis in science is to stop taking scientific articles too seriously. What matters is code, data, open protocols, pre-registration. Certainly not fact the article was endorsed by a publisher, especially predatory ones like Nature Publishing Co
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