Tissues may be soft, but there’s only one Kleenex Ultra Soft — the #1 ultra tissue*. Each tissue features 3 layers of silky-soft strength that's gentle on watery eyes and runny noses, making them perfect to use for pollen allergies, back to school season, and everything in between. Not only does Kleenex Ultra Soft comfort skin and help protect hands, but they're also allergist approved and hypoallergenic.