Jacob Miller: Curious what you think of the Barbas lab proposals that cyto and connectivity are deeply related? E.g., feedforward and feedback connections based on cortical types. Seems to be a nice unifying idea of why both matter in different ways and are related evolutionarily, etc: doi.org/10.1007/s004...

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Ben Hayden handle.invalid · Jan 22
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Jacob Miller handle.invalid
Curious what you think of the Barbas lab proposals that cyto and connectivity are deeply related? E.g., feedforward and feedback connections based on cortical types. Seems to be a nice unifying idea of why both matter in different ways and are related evolutionarily, etc: doi.org/10.1007/s004...
Jan 23, 2026 14:54
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Vinny Costa vincentcostaphd.bsky.social · Jan 23
Excellent point. And in addition Maria Medalla’s related studies showing that cytoarchitecture also relates to where and how projections synapse onto different neuronal elements to effect different elements of cognitive control pmc.ncbi.nlm.nih.gov/articles/PMC...
Anterior Cingulate Synapses in Prefrontal Areas 10 and 46 Suggest Differential Influence in Cognitive Control

Dorsolateral prefrontal areas 46 and 10 are involved in distinct aspects of cognition. Area 46 has a key role in working memory tasks, and frontopolar area 10 is recruited in complex multitask operations. Both areas are innervated by the anterior ...

pmc.ncbi.nlm.nih.gov

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