Sona C
Drug Discovery. Neuroscience. Technology. President, AI @ Pangea Bio
- Could overlooking sex differences be part of the reason for stalling in Alzheimer’s research progress? Fascinating that it disproportionately affect women who represent 2/3 of patients, and estrogen seems to play a major role. #Alzheimers #Neuro #womenshealth 🧠🧐 tinyurl.com/39xtveas
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- This is pretty damn cool, new research from stanford reports building an #agingclock of the #brain using #spatialtranscriptomics. Has interesting insights on how things like exercise and disease impact brain cell aging. www.nature.com/articles/s41...
- Reposted by Sona C"Why does the brain need billions of neurons to process 10 bits/second? Why can we only think about one thing at a time?" www.cell.com/neuron/fullt... From The Unbearable Slowness of Being
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- Interesting.. patients on GLP-1 agonists commonly report anhedonia as a side effect of these drugs
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- Insight into the #neurobiology of #addiction: Drugs like morphine boost myelination in dopaminergic neurons & the reward circuit, increasing signaling + reinforcing addictive behaviors. Conversely,blocking myelination reduced drug-seeking. Could be interesting for #therapeutics? tinyurl.com/ywznzdzn
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- If Vertex's suzetrigine is approved, it will be the first non-opioid (NaV1.8 inhibitor) for severe pain. Payors face a dilemma: stick w/ protocol of covering cheap but addictive generic opioids, or cover a safer, pricier branded option? #pain #therapeutic #neuro #pharma #biotech tinyurl.com/4byn7s92
- Can the therapeutic benefit of psychedelics be unlocked w/o the trip? Only time (& clinical studies) will tell. In mice, scientists managed to identify & reactivate the neural circuits for anxiety relief while bypassing those causing hallucinations. tinyurl.com/3c6v4w3v #neuroscience #therapeutics
