Sebastian Greenhough
Cell biologist and drug discovery scientist with Cancer Research Horizons. Based at the CRUK Scotland Institute in Glasgow.
- Super interesting and important PhD position available at Glasgow. Great supervision as well. www.findaphd.com/phds/project...
- We are currently recruiting for a Senior Scientist to join our translational biology team in Cambridge. Take a look! cancerresearchuk.wd3.myworkdayjobs.com/en-US/Extern...
- Nice paper just out from our NMR guys describing an accelerated method for measuring and scoring fragment binding affinities. pubs.acs.org/doi/10.1021/...
- Undergraduates, we are recruiting! Come and join us at the @cruk-si.bsky.social in Glasgow for your industrial placement year. Start date September 2026. Great lab, great people, great city. Take a look! cancerresearchuk.wd3.myworkdayjobs.com/en-US/Extern...
- Join us TODAY up on the Garscube artificial pitch at 1.15pm for Beatson Galaxy vs Wolfson Wolves, all in aid of Stand Up to Cancer. 60 minutes, 9v9, star-studded line-up. See you there! fundraise.cancerresearchuk.org/page/kick-of...
- A colleague is organising a charity football match next week to raise money for @su2c.bsky.social. It will feature some high-impact hotshots from @cruk-si.bsky.social and @uofgcancersciences.bsky.social so please take a look and come along if you can! fundraise.cancerresearchuk.org/page/kick-of...
- Organoids Are Us 2025 is happening at the Scotland Institute this week. I didn’t sign up but might sneak a look at the posters and/or buffet later.
- Things like this don’t surprise me, but I wish we could stop talking about biology in terms of rules. All we really have are models, which either have real-world applications or they don’t. Keep breaking those rules, ants.
- A common type of ant in Europe breaks a fundamental rule in biology: its queens can produce male offspring that are a whole different species go.nature.com/4mOb5T9
- Saw the number plate P53 APC today and can only assume that I work with whoever owns it.
- Read all about our small molecule pan-Ras inhibitors below! A 15-year effort from a team who still can’t get enough of near-impossible drug targets. I was only at the fringes of the project myself but pleased to have helped out here and there. Great work all!
- 🎉 Congrats to our scientists at The Scotland Institute on their publication in the Journal of Medicinal Chemistry! They’ve developed reversible Ras inhibitors with tunable affinity for active & inactive forms, a big step in #DrugDiscovery. More: tinyurl.com/y45t4yy7 #OnMyHorizon @acs.org
- Finishing out in style with a thought-provoking address from René Bernards on therapeutic overactivation of oncogenic signalling. A great final day with a strong showing for immunogenic cell death including the first clinical data I’ve seen combining IAP & PD-1 inhibitors. Exciting! #BACR2025
- All done with day 2 of #BACR2025. Lots of great immune stuff today - I believe neutrophils were mentioned more than 500 times but I’m here for it.
- Back in Edinburgh for day 2 of the BACR meeting. A bit nostalgic for my old commute, but I’m glad I don’t now have to get a bus to Little France. Or Roslin.
- Day 1 of the British Association for Cancer Research 65th Anniversary Meeting. Some good stuff on DNA repair, nonsense-mediated decay, epigenetics, dormancy, metabolism and lots more. Nice venue too - The Royal College of Physicians of Edinburgh. Back again tomorrow! @thebacr.bsky.social #BACR2025
- Enjoyed visiting the Crick for the first time this week. Also if you’re in the area and need a breather then the nearby stretch of Regent’s Canal is lovely.
- We are currently recruiting for a scientist with a background in cell biology or immunology. This is a permanent, lab-based position at our site in London. Take a look! cancerresearchuk.wd3.myworkdayjobs.com/en-US/Extern...
- If you’re looking for an exciting immuno-oncology postdoc position in a great city then I would advise applying for this!
- The Athena Swan Gold Award celebration was genuinely better than quite a few weddings I’ve been to.
- I’m very glad to have been able to help out with this as a member of the @scs-voice.bsky.social committee over the past few years. Great work everyone!
- I’m a little late to the party, but this is a great read.
- A case for broadening our view of mechanism in developmental biology Read this Perspective Article from B. Duygu Özpolat @biyolokum.bsky.social , Swathi Arur @swathiarur.bsky.social and Mansi Srivastava: journals.biologists.com/dev/article/152/2/d…
- Just registered for this. Should be good!
- We’re currently recruiting for a biochemist, to be based here in Glasgow at the @cruk-si.bsky.social or otherwise down in Cambridge. Take a look, and obviously choose Glasgow! cancerresearchuk.wd3.myworkdayjobs.com/en-US/Extern...
- Hi everyone, it’s been a while!
