Clément Cabriel

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CNRS researcher in Single-Molecule Localization Microscopy at Institut Langevin (ESPCI Paris / PSL University / CNRS).

Joined December 2024

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Emmanuel Margeat handle.invalid · Oct 17, 2025
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Ignacio Izeddin handle.invalid · Oct 15, 2025
Resolution improvement and multicolor demixing with event-based SMLM #EveSMLM by Manon Albecq and Clément Cabriel @clementcabriel.bsky.social #Mifobio2025 @gdrimabio.bsky.social

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Young French ChemBio fychembio.fr · Oct 1, 2025
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Ulrike Endesfelder handle.invalid · Sep 12, 2025
Please share: The application for Les Houches is open (until Oct 31) fluorescenceleshouches.wordpress.com *This is for you, if you ever wanted to learn all about fluorescence markers & how to apply them for your biological research!* PS: no fees this year, you just need to get there, that's all!
French-German WE-Heraeus-Seminar "Fluorescence markers for advanced microscopy : From photophysics to biology - 2026"

March 15-20 2026, Les Houches, France

fluorescenceleshouches.wordpress.com

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Heilemann Lab handle.invalid · Aug 27, 2025
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GdR ImaBio gdrimabio.bsky.social · Aug 26, 2025
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SMLMS 2025 handle.invalid · Jun 17, 2025
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Boris Vauzeilles borisvauzeilles.bsky.social · Jun 12, 2025
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SMLMS 2025 handle.invalid · Jun 11, 2025
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GdR ImaBio gdrimabio.bsky.social · Jun 3, 2025
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GdR ImaBio gdrimabio.bsky.social · Jun 4, 2025
📣 🔬 Save the Date – July 3rd in #Paris #France 🔬 📣 We’re excited to announce the first meeting of the #photoacoustic #imaging #working_group of #GDRImabio taking place on July 3rd at @sorbonne-universite.fr ✅ Free event – Register and submit your abstract here: 👉 shorturl.at/sLz9I

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GdR ImaBio gdrimabio.bsky.social · May 5, 2025
🔥It's D-day. We're opening pre-registration for #Mifobio2025 today🔥 👉 This is the 11th edition of the Thematic School! All the relevant information, as well as the pre-registration form, is easily accessible on imabio-cnrs.fr but only if you are logged on this site. 👉Deadline June 10, 2025 ❗

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SMLMS 2025 handle.invalid · Apr 7, 2025
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Société Française de Physique handle.invalid · Apr 4, 2025
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Clément Cabriel handle.invalid · Feb 12, 2025
Job alert: we have 2 offers! -PhD: a-synuclein mobility quantification in neurons. Co-supervision Christian Specht (INSERM, U. Paris-Saclay), @izeddinresearch.bsky.social shorturl.at/ifFVY Deadline 23/03 -Software/data processing engineer on Event-based SMLM shorturl.at/i5fcF Contact us for details
Synuclein diffusion analysis in neurons using event-based super-resolution microscopy (SEVEN) -

Synuclein diffusion analysis in neurons using event-based super-resolution microscopy (SEVEN) Thesis director Christian SPECHT christian.specht@inserm.fr SPECHT Christian Thesis director (CRCN), […]

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Clément Cabriel handle.invalid · Feb 6, 2025
Happy to share our new article: doi.org/10.1021/acsami.4c19431 We used multiscale fractal microstructured substrates with 3D #SMLM for calibration, cell culture and #superresolution. @instlangevin.bsky.social @espciparispsl.bsky.social @cnrs.bsky.social @utwente.bsky.social @uottawa.bsky.social
3D Single-Molecule Super-Resolution Imaging of Microfabricated Multiscale Fractal Substrates for Calibration and Cell Imaging

Microstructures arrayed over a substrate have shown increasing interest due to their ability to provide advanced 3D cellular models, which open up new possibilities for cell culture, proliferation, and differentiation. Still, the mechanisms by which physical cues impact the cell phenotype are not fully understood, hence the necessity to interrogate cell behavior at the highest resolution. However, cell 3D high-resolution optical imaging on such microstructured substrates remains challenging due to their complexity as well as axial calibration issues. In this work, we address this issue by leveraging the geometrical characteristics of fractal-like structures, which serve as axial calibration tools and modulate cell growth. To this end, we use multiscale 3D SiO2 substrates consisting of spatially arrayed octahedral features of a few micrometers to hundreds of nanometers. Through optimizations of both the structures and optical imaging conditions, we demonstrate the potential of these 3D multiscale structures as an alternative to electron microscopy for material imaging but also as calibration tools for 3D super-resolution microscopy. We used their multiscale and known geometry to perform lateral and axial calibrations in 3D single-molecule localization microscopy (SMLM) and assess imaging resolutions. We then utilized these substrates as a platform for high-resolution bioimaging. As a proof of concept, we cultivate human mesenchymal stem cells on these substrates, revealing very different growth patterns compared to flat glass. Specifically, the spatial distribution of cytoskeleton proteins is vastly modified, as we demonstrate with a 3D SMLM assessment.

doi.org

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Clément Cabriel

French-German WE-Heraeus-Seminar "Fluorescence markers for advanced microscopy : From photophysics to biology - 2026"

Synuclein diffusion analysis in neurons using event-based super-resolution microscopy (SEVEN) -

3D Single-Molecule Super-Resolution Imaging of Microfabricated Multiscale Fractal Substrates for Calibration and Cell Imaging