Han Yuan

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  Han Yuan handle.invalid · Jun 2, 2025
  1/ DNA sequence models like Borzoi predict gene expression and variant effects across tissues — but how can someone adapt the model to a custom experiment? @drkbio.bsky.social, Johannes Linder and I propose a solution via parameter-efficient fine-tuning (PEFT). www.biorxiv.org/content/10.1...
  

  Parameter-Efficient Fine-Tuning of a Supervised Regulatory Sequence Model

  DNA sequence deep learning models accurately predict epigenetic and transcriptional profiles, enabling analysis of gene regulation and genetic variant effects. While large-scale training models like E...

  biorxiv.org
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  Han Yuan handle.invalid · Jun 2, 2025
  2/ Code: github.com/calico/baske... Tutorial: github.com/calico/baske...
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  David Kelley drkbio.bsky.social · Apr 20, 2025
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  anyakors anyakors.bsky.social · Apr 16, 2025
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