Anchel de Jaime-Soguero
Cell and developmental biology enthusiast studying cellular communication. Group leader at IRIBHM-ULB, Belgium
- 🚨 PhD opportunity Interested in stem cells, mammalian development, and omics? The Migeotte & De Jaime-Soguero labs are recruiting a PhD student with bioinformatics background to work on embryonic and extraembryonic development. 🗓 Deadline April 2026 👇 Details below www.iribhm.org/open-positio...
- Reposted by Anchel de Jaime-Soguero🚨 Paper alert! The final version of our latest manuscript is published. We are excited to share this new resource for the zebrafish community and beyond: doi.org/10.7554/eLif... Congratulations to all authors! 🥳
- Reposted by Anchel de Jaime-SogueroBeautiful, thorough, personal in places, memoir of John Gurdon from Eddy de Robertis, disciple and friend. Å #MustRead about a generation and a time from which we have moved on but that laid the foundation for contemporary biology. www.sciencedirect.com/science/arti...
- Cellular signaling (BMP/SMAD) at the helm of chromosomal instability in cancer, similar as what we described during development and lineage specification. Congrats to our collaborators at the Bastians lab.
- SMAD4 loss drives cancer chromosomal instability through transcription-replication conflict-induced replication stress biorxiv.org/content/10.64898/20…
- ‼️‼️📢📢 Job Alert! Our lab at @iribhm.bsky.social - @ulbruxelles.bsky.social is seeking for a PhD student to work on the proteostasis of early mammalian development using stem cell models and the embryo. If you are enthusiastic about cell and dev biology, please apply!
- Excited to present our work tomorrow online at Social DNAing series. 18.00PM CEST time following the link below.
- Are you ready for the 2nd half of 2025? Social DNAing is ready. Check out the speaker list and schedule! Sign up at www.cancer.columbia.edu/research/pro...
- Reposted by Anchel de Jaime-SogueroThe modularity of the mammalian #embryo in display. Controlled assembly of classic #gastruloids and uncommitted precursors in #hypoxia, patterns the AP axis www.biorxiv.org/content/10.1... Beautiful & insightful from @bulutkarslioglu.bsky.social group. Building models to learn and learning.
- Reposted by Anchel de Jaime-SogueroCrick researchers have developed a new stem cell model of the mature amniotic sac development. The team is now exploring the potential for using these new 3D models in clinical applications, such as cornea reconstruction and treating ulcers. www.crick.ac.uk/news/2025-05...
- Reposted by Anchel de Jaime-SogueroJoin us tomorrow for our next seminar: 🗓️ Thursday, May 08 ⏰ 9:30 PDT / 12:30 EDT / 16:30 UTC / 17:30 BST / 18:30 CET
- Next Western 🌙 VGZT coming up: 🗓️ Thursday, May 08 ⏰ 9:30 PDT / 12:30 EDT / 16:30 UTC / 17:30 BST / 18:30 CET 👉 @ancheldjs.bsky.social (Regulation of chromosome segregation fidelity across lineage specification) 👉 @emmanuelhaillot.bsky.social (Mesoderm and endoderm formation in Nematostella)
- Looking forward to giving this talk next week!
- Next Western 🌙 VGZT coming up: 🗓️ Thursday, May 08 ⏰ 9:30 PDT / 12:30 EDT / 16:30 UTC / 17:30 BST / 18:30 CET 👉 @ancheldjs.bsky.social (Regulation of chromosome segregation fidelity across lineage specification) 👉 @emmanuelhaillot.bsky.social (Mesoderm and endoderm formation in Nematostella)
- Reposted by Anchel de Jaime-SogueroAneuploidy is the leading cause of pregnancy loss. In work led by @saracarioscia.bsky.social and @aabiddanda.bsky.social, we reanalyzed genetic testing data from 139,416 IVF embryos to discover variants associated with recombination phenotypes and aneuploidy risk. www.medrxiv.org/content/10.1...
- Last few months have been of change. I finished my postdoc at @cosheidelberg.bsky.social and moved to Belgium to begin my research group at @iribhm.bsky.social. I will reflect here my thoughts about the last years experience.
- I arrived to Sergio Acebrón lab in July 2019, and I have truly enjoyed Heidelberg vibrant environment since then. Great colleagues, tons of fun, research and also (sometimes) desperation, but a group caring for eachother overall. It made so easy to progress and develop my scientific ideas.
- @acebronsp.bsky.social thanks for being such inspiring mentor, for caring for your people and for sharing your vast knowledge and experience. Your commitment to make us improve at the personal and professional level has been pivotal. It has been a great ride!
- A new step has already begun. Happy to form part of @ulbruxelles.bsky.social and @iribhm.bsky.social community, and very much looking forward to developing my independent research lines on development and stem cell biology.
- Reposted by Anchel de Jaime-SogueroIn this Review, @eliananehme.bsky.social, @amiteshp.bsky.social, Isabelle Migeotte and @pasquelab.bsky.social give an overview of the embryonic origin and function of extra-embryonic mesoderm in vertebrates from in vivo studies. journals.biologists.com/dev/article/...
- Reposted by Anchel de Jaime-SogueroDo you want to illuminate your studies on innate immune responses? Our new biosensor monitors mtDNA from apoptosis, viral infections, other sources of dsDNA and environmental cGAMP. We also show that micro nuclei are poor activators of the #STING response
- SIRF: Sergio Acebron @acebronsp.bsky.social @cosheidelberg.bsky.social and colleagues develop a new #biosensor reporting on functional interactions between dsDNA sensor STING and #IRF3, allowing to capture STING activation upon various triggers www.embopress.org/doi/full/10....
- Reposted by Anchel de Jaime-SogueroSAVE THE DATE! The next EMBO | EMBL Symposium on 'DNA replication and genome maintenance: from basic biology to disease' will be held October 20-23, 2026. Organized by Helle Ulrich (IMB), Johannes Walter (Harvard) and Anja Groth (Danish Cancer Institute). www.embl.org/about/info/c...
- Design of a STING fluorescent real time biosensor. Tour de force of my colleague #Steve under Sergio @acebronsp.bsky.social supervision. 👏👏👏
- SIRF: Sergio Acebron @acebronsp.bsky.social @cosheidelberg.bsky.social and colleagues develop a new #biosensor reporting on functional interactions between dsDNA sensor STING and #IRF3, allowing to capture STING activation upon various triggers www.embopress.org/doi/full/10....
- Novel insights on cellular signaling regulation of DNA replicative dynamics. BMP signaling not only prevents from replicative stress in pluripotency, as we described recently (www.nature.com/articles/s41...) but also drives regeneration through same mechanisms. www.nature.com/articles/s41...
- Reposted by Anchel de Jaime-SogueroSurprisingly we find that as few as 2 starting p53KO cells will compete in an environment of @300 WT cells. Also, see an input for BMP & Wnt signalling that mirrors work on the control of chromosomal segregation in stem cells www.nature.com/articles/s41...
- Great work on cell competition during mammalian gastrulation. It aligns with our observations on chromosome stability-driven by morphogens and open further questions on the relation of cellular fitness and genome integrity. Congrats!
- 1/3 Embryogenesis requires fit cells. Here, following work from @miguel-torres-1963.bsky.social & @tristanrodriguez72.bsky.social and led by @joshifrenster.bsky.social we develop a #gastruloid model of #CellCompetition www.biorxiv.org/content/10.1... showing it recapitulates much of the embryo 🧵
- Great city, great environment and cool projects (including stem cell modelling, development, homeostasis and cancer biology). Have a look to the research groups offer and do not hesitate to apply!
- 🎉 We’re pleased to announce the launch of the IRIBHM Jacques E. Dumont International PhD Programme 2025! A great opportunity to shape the future of biomedical sciences by preparing the next generation of leaders. 🚀 Don’t miss your chance to be part of this innovative adventure! iribhmphd.ulb.be
- Reposted by Anchel de Jaime-SogueroGreat opportunity for a PhD in Brussels. Outstanding mentor and project addressing bottlenecks in human development
- 🚨 🚨 Job Alert! I am currently opening my research lab at @iribhm.bsky.social @ulbruxelles.bsky.social in Belgium and I am seeking for an enthusiastic PhD candiate to study cellular stress across mammalian development and lineage specification! If you are interested, info below. Please RT!
- ⚠️📢 Few weeks to close the call. If you love cell & devbio, and are interested on doing a PhD in stress resilisence, please APPLY!
- 🚨 🚨 Job Alert! I am currently opening my research lab at @iribhm.bsky.social @ulbruxelles.bsky.social in Belgium and I am seeking for an enthusiastic PhD candiate to study cellular stress across mammalian development and lineage specification! If you are interested, info below. Please RT!
- Gracias a Pilar Perla y @heraldo.es por la difusión de nuestro trabajo en el lab de Sergio Acebrón @acebronsp.bsky.social y mi opinión sobre la investigación básica en mi tierra, Aragón. www.heraldo.es/noticias/ara...
- Reposted by Anchel de Jaime-SogueroRegistration is open for the 12th Advances in Stem Cell Biology Course #ASCBcourse at the @pasteur.fr Hands-on training in different models, embryonic stem cells, iPS cells and much more on #StemCells. 🕘June23-July04, 2025 👉https://qrfy.io/VEcoKQpGfV
- Reposted by Anchel de Jaime-Soguero🚨 🚨 Job Alert! I am currently opening my research lab at @iribhm.bsky.social @ulbruxelles.bsky.social in Belgium and I am seeking for an enthusiastic PhD candiate to study cellular stress across mammalian development and lineage specification! If you are interested, info below. Please RT!
- Reposted by Anchel de Jaime-SogueroApplications open for a new cohort of @dev-journal.bsky.social *Pathway to Independence* fellows Know a #devbio post-doc about to enter the academic job market? Would they benefit from a little support & mentoring? Spread the word Deadline 31 Jan 2025 journals.biologists.com/dev/pages/pi...
- What a day! An honour to present our work next to these giants and the dynamic belgian stem cell researchers. Great to be back!
- It was a fantastic edition of the 8th Meeting of the Belgian Society for Stem Cell Research in Brussels with stellar speakers including Susana de Sousa Lopes, Jacob Hanna, Florian Merkle, Anchel de Jaime-Soguero and many more. Thank you to all participants. #BeSSCR #StemCells
- Reposted by Anchel de Jaime-SogueroIt was a fantastic edition of the 8th Meeting of the Belgian Society for Stem Cell Research in Brussels with stellar speakers including Susana de Sousa Lopes, Jacob Hanna, Florian Merkle, Anchel de Jaime-Soguero and many more. Thank you to all participants. #BeSSCR #StemCells
