Lingyin Li Lab
The lab of chemical immunology 🧬 🧫 💊 🐀 at Stanford University & Arc Institute.
Student-run account by the lab of Lingyin Li (@lingyinli.bsky.social)
lingyinlilab.stanford.edu
- This paper is now online at @cp-cellrepmed.bsky.social! Congratulations to all the authors. Read the paper here: www.cell.com/cell-reports...
- How can we do better with cancer immunotherapy? By leveraging both adaptive and innate immunity: in our latest preprint, we and industrial partners provide the most comprehensive characterization to date of STF-1623, an inhibitor of the innate immune checkpoint ENPP1 www.biorxiv.org/content/10.1...
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- The newest paper from the lab is now out @natchembio.nature.com! A hard-won effort by Rebecca and @xujunc.bsky.social uncovers a previously undescribed post-translationally modified site that regulates STING signaling and proposes a new strategy for inhibition. www.nature.com/articles/s41...
- In the latest Research Matters feature, @lingyinli.bsky.social discusses her quest for more broadly efficacious cancer therapies and the importance of learning from failures. news.stanford.edu/stories/2025...
- It's been a busy week for the Li lab! The 10th PhD in 10 years, @xujunc.bsky.social successfully defended his thesis! Congratulations, and keep an eye out for his work on new STING inhibitors and regulators!
- How can we do better with cancer immunotherapy? By leveraging both adaptive and innate immunity: in our latest preprint, we and industrial partners provide the most comprehensive characterization to date of STF-1623, an inhibitor of the innate immune checkpoint ENPP1 www.biorxiv.org/content/10.1...
- The ninth PhD defense from the lab by @songnanwang.bsky.social, now forging ahead with her MD-PhD! Excited for great things from Songnan yet to come!
- Reposted by Lingyin Li LabNew preprint: The first whole-body map of both DNA methylation and 3D genome organization at single-cell resolution across 16 human tissues, with in-depth analyses of cell type diversity of these epigenome modalities at unprecedented resolutions. (1/5)
- Rebecca Chan kicked off March for the lab by successfully defending her thesis! Watch this space for the newly minted Dr. Chan's phenomenal work on molecular mechanisms of STING signaling!
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- We're excited to share that our fearless leader @lingyinli.bsky.social has been promoted to full Professor of Biochemistry! Here's to decades more of research in therapeutics harnessing the innate immunity!
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- Reposted by Lingyin Li LabSeeking pioneering scientists in immunology, neuroscience, and machine learning! Join Arc Institute as a Core Investigator + Stanford Bioengineering as Associate/Full Professor. Full lab funding and cutting-edge facilities in Palo Alto. Apply by Jan 15 for full consideration: shorturl.at/CuH1K
- Happy holidays from the Li lab!
- Reposted by Lingyin Li LabToday we report that an engineered skin bacterium, swabbed gently on the head of a mouse, can unleash a potent antibody response against a pathogen. Could lead to topical vaccines that are applied in a cream. @djenetbousbaine.bsky.social led the charge... @natureportfolio.bsky.social 1/55
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- The Li lab is at the Cell Symposium @cellpress.bsky.social! Lab leader @lingyinli.bsky.social presents the lab's work on new therapeutic modalities harnessing the STING pathway
- Graduate students Rebecca Chan and Xujun Cao (@xujunc.bsky.social) present posters on mechanistic work underlying STING activation and the development of inhibitors. Read their preprint here: www.biorxiv.org/content/10.1...
