Jason da Silva Castanheira
The guy in the pink suit at OHBM 🧠🧠🧠
Postdoc Fellow at the Division of Psychology and Language Sciences, UCL
- Reposted by Jason da Silva CastanheiraNow in press one of my last PhD projects! We traced the neurobiological profile of fMRI BOLD signal variability, a measure that has been related to age, behaviour, disease status, but had not yet been fully contextualised within the brain's multiscale architecture. www.nature.com/articles/s41...
- Very proud to announce that the final chapter of my thesis is now out in Cell Reports! How do neurophysiological traits that characterize individuals evolve across the lifespan? We combined data from over 1,000 individuals aged 4–89 to answer this question. (1/6) 🧠👶👦👧👱👩🦱🧔♂️🧓👴 doi.org/10.1016/j.ce...
- People’s brain activity is much like a fingerprint and can distinguish individuals from one another. But all of this work has been done, for the most part, in adults. What about children and older adults? (2/6)
- Children 👦👧 were more difficult to distinguish from one another based on their neurophysiology than adults. This is because children's neurophysiological traits are more similar to one another. Arrhythmic brain activity drives this effect—children are differentiable from rhythmic brain traits. (3/6)
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View full threadThank you so much to the brilliant @sylvainbaillet.bsky.social and @alexwiesman.bsky.social for all their support. And to our wonderful collaborators at @sickkidsto.bsky.social Margot Taylor! (6/6)🌈
- Quantifying rhythmic and arrhythmic brain activity is a hot 🥵 topic. But how independent are the two components from one another? 🤔 In my latest work with @smfleming.bsky.social & @matlandry.bsky.social, I explore the relationship between the two. (1/4)
- Brain rhythms are important! 🚨Peristimulus alpha power predicts participants’ subjective experience. 👀 Arrhythmic brain activity is equally important! Both are theorized to be markers of cortical inhibition⚡️. But can we measure the two independently of one another with our current tools? (2/4)
- We show that spectral detrending methods produce biased estimates of rhythmic power that introduce spurious correlations between brain rhythms and arrhythmic brain activity. Modelled Gaussian power, on the other hand, does not. 🤯 (3/4)
- Using an empirical dataset, we show that analytical choice in quantifying brain rhythms impacts the interpretation of your results! 😰 Lastly, we find that resting state alpha power and arrhythmic slope are positively correlated at rest, which dovetails with the cortical inhibition account. (4/4)
- Reposted by Jason da Silva CastanheiraNew study ✨! ⍺ regulates perceptual switches during binocular rivalry: ⍺↓ before dominant percepts, ↑ before mixed percepts + PO connectivity shifts from top-down to feedforward after perceptual alternations Led by Janine Mendola @mcgill.ca, w/ E Mokri & @jasondasilvac.bsky.social
- 🚨The first paper of my postdoc is out now in @elife.bsky.social! 🚨 We explored the role of attention in planning. Thank you 🙏 to the reviewers for their helpful comments & suggestions. Keep your 👀 peeled for additional analyses and our response. elifesciences.org/reviewed-pre...
- Reposted by Jason da Silva Castanheira🧠 New preprint: Why do deep neural networks predict brain responses so well? We find a striking dissociation: it’s not shared object recognition. Alignment is driven by sensitivity to texture-like local statistics. 📊 Study: n=57, 624k trials, 5 models doi.org/10.1101/2025...
- Reposted by Jason da Silva CastanheiraAfter five years of confused staring at Greek letters, it is my absolute pleasure to finally share our (with @smfleming.bsky.social) computational model of mental imagery and reality monitoring: Perceptual Reality Monitoring as Higher-Order inference on Sensory Precision ✨ osf.io/preprints/ps...
- Very proud to share this one🥹! We show that personalized signatures of brain activity are heritable and relate to the expression of specific genes. That means my brain-fingerprint is very similar to my twin brother's! #ResearchIsMeSearch🧠 🧬 ♊️
- Reposted by Jason da Silva Castanheira🧬🧠 Our latest study shows that individual brain dynamics are partly written in our genes. We found that heritable neurophysiological traits align with adult cortical gene expression and psychological function. www.science.org/doi/10.1126/... @theneuro.bsky.social @mcgill.ca
- Reposted by Jason da Silva CastanheiraCollecting an extensive publicly available dataset on 4 inhibitory control tasks, Lee et al. show that more than 1000 trials/participant are necessary to reduce within-subject variability and improve the reliability of the congruency effect. www.nature.com/articles/s41...
- 🚨Excited to share my first preprint from my postdoc with @smfleming.bsky.social! 🚨 We explore how attention shapes simplified mental representations for planning. We show that inductive biases characteristic of attentional selection shape how we plan. Check it out: osf.io/preprints/ps... 🧠🔦🤖
- Reposted by Jason da Silva CastanheiraWant to present at MEG-UKI but funding is a barrier? We’re offering a limited amount of travel bursaries for presenters to help cover the cost of: - Registration - Accommodation - Travel expenses Click the link below to find out more: meguk.ac.uk/apply-for-bu...
- Reposted by Jason da Silva CastanheiraDeadline approaching, only 6 days left! Follow the link below to submit your abstract: meguk.ac.uk/abstract-sub...
- Reposted by Jason da Silva CastanheiraDrumroll please... 🥁 Abstract submission for MEG-UKI 2025 is now open!!! All the details can be found meguk.ac.uk/meg-uki-2025/ We are looking forward to welcoming you to London!
- How do neurophysiological traits that characterize individuals evolve across the lifespan? Check it out: 👶🧒🧑🧓🧠 with the amazing @sylvainbaillet.bsky.social @alexwiesman.bsky.social & Margot Taylor www.biorxiv.org/content/10.1... 🧵(1/3)
- We analyzed resting-state MEG from over 1000 individuals between the ages of 4 and 89: -children are harder to differentiate from one another 👯♂️ based on arrhythmic brain activity. 🧠 - rhythmic activity remains a reliable marker of individuality across all ages🌈. 🧵 (2/3)
- -Sensorimotor cortices 🏋️♀️🚴♀️ become increasingly prominent for differentiating individuals across neurodevelopment and aging. -These changes become increasingly aligned with cortical gene expression🧬. 🧵 (3/3)
- Reposted by Jason da Silva CastanheiraNew preprint! 📢 We combine MEG and neuromelanin-sensitive MRI of the locus coeruleus to show a noradrenergic basis for altered alpha rhythms in #Parkinson's disease w/ Victoria Madge, Ted Fon, Alain Dagher, Louis Collins, and @sylvainbaillet.bsky.social www.medrxiv.org/content/10.1...
- Reposted by Jason da Silva CastanheiraCongrats to newly minted Dr. Jason da Silva Castanheira! @jasondasilvac.bsky.social 🧑🎓!!!
- As if my name isn’t long enough already, I added PhD to it today!
- Reposted by Jason da Silva CastanheiraWe are recruiting for a Marie Curie "CODE" PhD student 💻🧠🚨 (sites.google.com/view/confide...) The project will focus on neurocomputational approaches to information seeking, offloading and metacognitive control across the lifespan www.ucl.ac.uk/work-at-ucl/... Deadline 22 Feb, pls share!
- Reposted by Jason da Silva CastanheiraNew paper(!) on the neurochemistry of structural and functional cortical changes in #Parkinson's disease w/ fantastic collaborators @jasondasilvac.bsky.social Ted Fon and @sylvainbaillet.bsky.social Now published OA in @ANA_journals: 📰https://doi.org/10.1002/ana.26871 🧵👇 (1/8)
- Reposted by Jason da Silva CastanheiraPostdoc in our lab! Last day to apply! Please apply if interested - don’t worry about supporting docs or anything. (Apologies for the awkward timing on the deadline - it was an HR thing.)
- ! Job alert ! Our postdoc position at the UCL Learning Memory & Decision lab is open for applications! Please see the ad here: t.ly/gLGHu The ad currently closes on January 2nd. Experts in memory or decision-making and imaging (& behavior), please apply! See thread below. Please share!
- Initial submission of my PhD thesis ✅ If Mariah Carey tops the Spotify charts next week, y’all will know why… #AllIWantForChristmasIsAPhD
- Reposted by Jason da Silva CastanheiraNew collab work driven by the magic duet @matlandry.bsky.social + @jasondasilvac.bsky.social just published in @OxUniPress Cerebral Cortex. Parsing out the neurophysiological substrates of ⬆️ vs. ⬇️ attention.
- Our work on how modulations of lateralized alpha-band activity partly mediate the interference of exogenous attention over endogenous attention processing. academic.oup.com/cercor/advan... w/ the exceptional @jasondasilvac.bsky.social, Amir Raz, Jerome Sackur, & @sylvainbaillet.bsky.social
- Very excited to share this work (it’s been a long time in the making). Here we show that both top-down 📖 and bottom-up ‼️attention modulate 🧠alpha-band activity, which partially explains the interference between the two attention systems when oriented 👀to opposite spatial locations.
- Our work on how modulations of lateralized alpha-band activity partly mediate the interference of exogenous attention over endogenous attention processing. academic.oup.com/cercor/advan... w/ the exceptional @jasondasilvac.bsky.social, Amir Raz, Jerome Sackur, & @sylvainbaillet.bsky.social
- Went to see Mariah Carey’s Christmas show and submitted a manuscript this week. I’m feeling accomplished! 😌
- Reposted by Jason da Silva CastanheiraRelationships between brain signal variability and executive function change as a function of life stage. So glad to finally get this out! direct.mit.edu/netn/article...
- So happy to be a part of this paper! Go read all about our results. A big OBRIGADO to @AlexWiesman for including me 😇😌
- New paper from our Parkinson's research, now out in Progress in Neurobiology: doi.org/10.1016/j.pn... w/ @jasondasilvac.bsky.social Ted Fon, Clotilde Degroot & @sylvainbaillet.bsky.social We demonstrate multi-frequency slowing of cortical neurophysiology in patients with Parkinson's disease 🧵👇
- Reposted by Jason da Silva CastanheiraHello Bluesky/Twitter refugees! For my first post, I invite you to check out the latest work by @garedaba.bsky.social and myself where we look at thalamocortical gradients in human and mouse brains 🌈🧠🐭🌈 In short, we highlight evidence for a supra-nuclear axis of thalamocortical organisation
- Reposted by Jason da Silva CastanheiraIntegrating multimodal and multiscale connectivity blueprints of the human cerebral cortex in health and disease journals.plos.org/plosbiology/... #neuroimaging #neuroscience
- Reposted by Jason da Silva CastanheiraI think I just created a feed for EEG in neuroscience. Add #EEG to your EEG or MEG related posts to make it appear in the feed. bsky.app/profile/did:...
