Manuela Raffatellu: Here's the link to the companion paper: journals.asm.org/doi/10.1128/... - together, our studies show that PgtE enables Salmonella to evade innate immunity and cause bacteremia.

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Manuela Raffatellu handle.invalid · Jul 15, 2025
Happy that our manuscript showing that PgtE protease enables Salmonella to evade C3-mediated serum and neutrophil killing is published in mBio journals.asm.org/doi/10.1128/... - check out the companion paper from @rtsolis.bsky.social and team, focused on PgtE in the African Salmonella strain ST313
PgtE protease enables virulent Salmonella to evade C3-mediated serum and neutrophil killing | mBio

Non-typhoidal Salmonella serovars primarily cause gastrointestinal infections but can also lead to bacteremia through mechanisms that are not completely elucidated. Here we show that the outer membran...

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Manuela Raffatellu handle.invalid
Here's the link to the companion paper: journals.asm.org/doi/10.1128/... - together, our studies show that PgtE enables Salmonella to evade innate immunity and cause bacteremia.
African Salmonella enterica serovar Typhimurium ST313 isolates prevent reactive oxygen species production by human neutrophils via elevated PgtE expression | mBio

The S. enterica serotype Typhimurium omptin family protease PgtE has long been known to cleave complement factors bound to the bacterial surface, but a role for complement inactivation by PgtE in avoidance of serum bactericidal activity was found only for ...

journals.asm.org
Jul 15, 2025 19:00
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