Darragh O'Brien
Translational Proteomics & Neurodegenerative Disease at the University of Oxford. Tauopathy & Dementia. Protein structural plasticity, modification, and clearance. Research Fellow of Green Templeton College.
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- Reposted by Darragh O'BrienYesterday's sunset 🌅 📷 Instagram | 12AtOxford
- Had a great time representing the Human Brain Proteome Project during the "Friends of HUPO" social at #HUPO2025 last night. If you want to get involved, or simply hear more about the initiative, please get in touch 🧠
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- Reposted by Darragh O'BrienNEW: We’re honoured to be ranked number one in the Times Higher Education World University Rankings for the tenth consecutive year. 👏
- Many thanks for the spotlight! "Trasna na dTonnta" (Across the Waves) is a great initiative from @drni.bsky.social for the Irish dementia research diaspora – a global community linking Irish dementia researchers on the island of Ireland to those undertaking research abroad #brainwaves 🧠🌊
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- A great story to be part of! Kudos to Mária, Anna, Anne, Sally and all of the team🧠
- Encaenia 2025 @ox.ac.uk with my 🧠 buddy @stephfowler.bsky.social. It was great to see fellow Enniscorthy native Colm Tóibín receive the honorary degree of Doctor of Letters for his contribution to literature and journalism 💜💛
- Fantastic start to the day here at the 3rd "Human Proteome and Health" Symposium at Rhodes House where Dr Katerina Gospodinova from the ARUK-ODDI and @cmd.ox.ac.uk discussed proteomic profiling of the #matrisome for use a novel therapeutic modality in #Alzheimers Disease 🧠 @arukthamesv.bsky.social
- Our review is out now in Molecular & Cellular Proteomics! We discuss the latest advances in #HDX mass spectrometry to aid neurotherapeutic design & development in #Alzheimers, #Parkinsons and #ALS, providing molecular insights into protein aggregation pathways and therapeutic antibodies 🧠
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- Reposted by Darragh O'BrienCheck out our June issue! www.nature.com/neuro/volume...
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- Reposted by Darragh O'Brien"Science is an investment. We will put forward a new 500 million package for 2025-2027 to support the best and the brightest researchers and scientists from Europe and around the world." — President @vonderleyen.ec.europa.eu at the ‘Choose Europe for Science' event at La Sorbonne 🇫🇷
- Wendy is an excellent scientist. I would highly encourage you to apply!
- Reposted by Darragh O'BrienNew research led by @marcaurelbusche.bsky.social has found that tau specifically disrupts a certain type of electrical activity in the hippocampus in Alzheimer's🧠 The findings unlock a key piece of the puzzle in understanding how toxic tau drives memory problems👏👉 buff.ly/yx8Rdk6
- Reposted by Darragh O'BrienHow does the brain repair myelin after injury? We mapped the full cellular choreography of white matter repair using snRNA-seq + Slide-seqv2, uncovering a type I interferon-driven glial program that recruits lymphocytes to promote remyelination. www.biorxiv.org/content/10.1... Details below 👇
- It's been a couple of weeks since finishing the Paris Marathon to raise funds for dementia research. I have finally recovered! What a day! Shout out to my running buddy Tika Malla and the ARUK cheer team who came to France. There's still some time to donate to our fundraising here shorturl.at/ujnKc
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- Go, Go, Go!
- Only 16 days to go until Paris! Please share the link and donate to help me raise urgent funds for dementia research 👇🏻 www.justgiving.com/page/26miles...
- Happy to announce that I'm now a Research Fellow of Green Templeton College, University of Oxford!
- Proudly flying the @alzresearchuk.bsky.social flag today at the Teddy Hall Relays in Oxford @cmd.ox.ac.uk @ndm.ox.ac.uk #foracure
- Reposted by Darragh O'BrienNow is the moment!! If you'd like to come and do a PhD with me in sunny Dundee then I have not 1 but 2 funded PhD positions in my lab looking at #ApoE. Please reach out with any questions! Come do science with us, it'll be fun! www.dundee.ac.uk/phds/opportu... www.dundee.ac.uk/phds/opportu...
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- Had a great time at #ARUKConf2025 hearing about exciting new directions for dementia research in the UK and beyond. It's always a great opportunity to catch up with old friends and colleagues and to make some new ones! #foracure
- A dark, wet and cold start, but well worth it! #foracure
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- I've #justsponsored Selina Wray, who's fundraising for Alzheimer's Research UK on @JustGiving. Donate now: www.justgiving.com/page/selina-...
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- Our Tau EV work made the cover. Such a beautiful image!
- Reposted by Darragh O'BrienApply as Transition Fellow in Brain Tumour Research @edinburghuni.bsky.social and @ucl.ac.uk ! 📢 Develop your independent research programme 💡 Collaborate with world-class experts for info contact Steven Pollard, Simona Parrinello, Vincenzo D'Angiolella #ResearchJobs #BrainCancer #CareerOpportunity
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- Reposted by Darragh O'BrienExciting new discovery from colleagues @stanfordmedicine.bsky.social, astrocyte metabolism compromised by amyloid and tau oligomers leading to insufficient support for neurons. Possible new target for treating AD. www.science.org/doi/10.1126/...
- Reposted by Darragh O'BrienOne week left to apply for this job!! I'm looking for a research tech to come and work on Alzheimers and ApoE! If you love cell culture, astrocytes, APOE or just fun science with fun people then come do science with us in beautiful Dundee! tinyurl.com/a33kjn49 Seriously the sunsets are on point!
- Reposted by Darragh O'Brien🧠Sharing this Starter Pack again as the list has now reached 80 people! A great mix of Profs/PIs/Post-docs/PhDs/Technicians. Please re-post so it can reach a wider audience as I'm sure there are more of us out there ☺️🦋 go.bsky.app/S6FfsTpat://did:plc:6dmicoi6v6mbpt4vqryba5tb/app.bsky.graph.starterpack/3lakmcrws6o2j
- Interesting cycle to work this morning 🥶
