Sina Neyazi

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  Masashi Nomura masashi-nomura.bsky.social · May 9, 2025
  1/ Thrilled to share our TWO back-to-back papers published in Nature Genetics today! www.nature.com/articles/s41... , www.nature.com/articles/s41...
  

  The multilayered transcriptional architecture of glioblastoma ecosystems - Nature Genetics

  Integrated single-cell transcriptomic and genetic characterization of 121 adult glioblastomas identifies heterogeneity at cell type, cell state and baseline expression program levels associated with s...

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  Sina Neyazi handle.invalid · May 2, 2025
  Exciting new work from our lab characterizing the immune cell landscape in pediatric high-grade glioma and ependymoma and revealing immune-suppressive changes following treatment! Biggest congratulations to Rebecca, Jenna and Mariella! 🥳
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    Cell Reports Medicine handle.invalid · May 1, 2025
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  Sina Neyazi handle.invalid · Mar 13, 2025
  Thrilled to share our work with Mariella Filbin, Johannes Gojo and Carl Koschmann, now published in @cp-cancercell.bsky.social We present a translational approach identifying the PDGFRA inhibitor avapritinib as a novel targeted treatment for pHGG with PDGFRA alterations www.cell.com/cancer-cell/...
  

  Effective targeting of PDGFRA-altered high-grade glioma with avapritinib

  PDGFRA is commonly altered in pediatric HGG. Mayr et al. report that the PDGFRA/KIT inhibitor avapritinib demonstrates on-target activity, brain penetrance, and survival benefit in pre-clinical H3K27M...

  cell.com
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  Sina Neyazi handle.invalid · Mar 1, 2025
  Very impressive, rapid intraoperative methylation classification for brain tumors in under 1 hour
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    Saheli Sadanand sahelisadanand.bsky.social · Feb 28, 2025
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