Alex Dickson
Developing new methods for molecular simulation. Likes: Data vis; ML; drug discovery; semicolons.
- Reposted by Alex DicksonParticularly of interest to people who want to do protein design in an academic environment w/ many colleagues in basic science (cancer biology, cell signaling, immunology, virology) & clinicians who can drive the discovery of new targets for hard-to-treat diseases & bring therapeutics to patients.
- The Cancer Signaling & Microenvironment Program at Fox Chase Cancer Center is looking for tenure track faculty (assist./assoc./full) in computational & experimental protein design. CV & 3-page research statement by Feb 15. More info here: www.linkedin.com/feed/update/... Questions: DM/Email me.
- Wow this piece is amazing! It would be even more entertaining if the future of the NIH wasn't hanging in the balance..
- Reposted by Alex DicksonHoly shit. Game 7 between the Jays and the Mariners just ran an pro-free trade ad, targeted to American workers, decrying tariffs. The twist being that, if you don't catch it beforehand, Ronald Reagan is revealed as the speaker in the closing seconds. What PAC is this? The Province of Ontario.
- A while ago a colleague led us through an exercise where we brainstormed a network of mentors. These could be anyone in the world who influenced the way we teach, communicate, do research or service. I wrote Daniel Naroditsky in all caps. I was floored yesterday to learn of his passing.
- Just gonna leave this here.. youtube.com/shorts/rx3SZ...
- Today I asked someone "what shape is your loss?" and I think that could really be a question for everybody
- BatchNorm is evil. Pure Satan spawn sent to destroy us and our projects 👿
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- A watched model never trains
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- This band has a bright future I can sense it youtu.be/CJ54eImz88w?...
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[Not loaded yet] - Our Flexible topology pocket explorer paper is up on ChemRxiv! doi.org/10.26434/che... We run simulations in the B2AR receptor and show that the Flexible Topology particles capture aspects of known B2AR ligands. We also show how FT frames can be used for screening to find new hits!
- I asked my kids to sing the Canadian national anthem, and they started off to the tune of "O Christmas Tree" 😬
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- Flexing some old vector geometry muscles 😅
- When you find the perfect photo..
- Had a really great time presenting our Flexible Topology work to the folks at Qubit! @qubit-pharma.bsky.social vimeo.com/992123602
- Reposted by Alex DicksonI have confirmation from several sources now that all T32s, many F30s and F31s, and most or all Center awards (P30, P50) have been terminated at Columbia. This is quite damaging to research and to individuals. This is pure terrorism and cannot be legal. But litigation will take time...
- I finally did it! 10k unread emails! Wow. What can I say?.. I couldn't have done this alone. It's been a long road. There's so many people I'd like to thank...
- I must be growing as a person, since I just managed to register for the ACS COMP social more than two hours ahead of time. Hope to see you there! urldefense.com/v3/__https:/...
- If you're looking for a socially responsible (and stable!) investment, check out $BGRN. It is a green bond ETF that funds environmental sustainability projects around the globe. Yields 4% per year which isn't bad!
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- What's easier to learn: cryo-EM or MD simulations? Ben Orlando and I couldn't decide, so we are accepting post-doc applications from both fields! Come work with us to explore the intersection between cryo-EM and MD at Michigan State! careers.msu.edu/jobs/researc...
- We've embedded a diffusion model inside an MD simulation 🤓! Very happy to share this as it has been a long road to get here. More to come! vimeo.com/1055522578
- Reposted by Alex Dickson🎉 Big news! 🎉 Together with Jianing Li (Purdue Univ.) & John Shelley (@schrodingerinc.bsky.social), I’m organizing a symposium on #CG #Modeling for Molecular & Formulation Design at ACS Fall 2025 (Aug 17-21, Washington, DC)! 🔬✨ For my part, I am grateful for the support of @ensdelyon.bsky.social!
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- Random chemistry question 🧪: what is a small organic molecule that exhibits a well-documented conformational change in two different solvents?
- So far I found a lot of work on 1,2-dichloroethane, which is roughly 8-fold trans:gauche in apolar solvents (e.g. cyclohexane) and roughly 50-50 (somewhat unclear?) in water
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- Any millennials out there listening to new music? Whaddyagot?
- A non-confrontationalist's guide to dealing with administrative overreach: 1) smile 2) "yes, we're exploring that" 3) "well, there are a lot of moving parts.." 4) go back to work
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