André Dias
Developmental biologist @AMAlab @upf. Playing with cells & genes to understand the role of signalling during mammalian gastrulation. PhD @IGCiencia
- Reposted by André DiasLovely little pre-Christmas present to see this out @natcellbio.nature.com! Some 🔥 new results in here since the biorvix incl (1) a new RARE-GFP reporter ✳️🙌, (2) additional NMP quantification 🔢, (3) no neural tube patterning on RA inhibition 🙅 etc. Enjoy! 😍 www.nature.com/articles/s41...
- Reposted by André DiasThe power of the media: core culture conditions direct gastruloid development This Research Highlight showcases the work from Tina Balayo, André Dias @dias-andre.bsky.social, David Turner @gastruloids.bsky.social and colleagues: journals.biologists.com/dev/article/...
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View full threadReposted by André DiasTo find out more about this work and the people behind it, we spoke to first author Tina Balayo, and to co-corresponding authors André Dias @dias-andre.bsky.social and David Turner @gastruloids.bsky.social: journals.biologists.com/dev/article/...
- We would like to thank the reviewers for their inputs, the editor, and @dev-journal.bsky.social for the interview journals.biologists.com/dev/article/... and the highlight journals.biologists.com/dev/article/...
- Now out in @dev-journal.bsky.social Lots of new results! Check it out!! journals.biologists.com/dev/article/...
- Reposted by André DiasI do like the @dev-journal.bsky.social "Research Report" format for shortish papers This one is valuable. "Is it the N2B27?" is the stem cell biologist version of "Is it the magnesium?" Congrats Tina Balayo @dias-andre.bsky.social David Turner & all authors journals.biologists.com/dev/article/...
- Now out in @dev-journal.bsky.social Lots of new results! Check it out!! journals.biologists.com/dev/article/...
- Reposted by André DiasHappy to present the final version of our Cadherin and gastruloid manuscript, online at @cp-cellreports.bsky.social. www.cell.com/cell-reports... Initially in BiorXiv (www.biorxiv.org/content/10.1...) 1/12
- Reposted by André Dias🚨JOB ALERT🚨 FRIENDS PLEASE SPREAD and RT We are building a small expert team within the @bokelab.bsky.social at @crg.eu @prbb.org to investigate fundamental questions in oocyte cell biology, focusing on how proteostasis regulation influences dormancy and fertility. See below 2 calls👇
- Reposted by André DiasTHANK YOU for many years of friendship, support and for sharing your great Science La Pedrera #Barcelona #NotInTheGenes #CellsRUs #Cambridge
- Reposted by André DiasGreat opportunity to join the vibrant developmental biology in Toronto (and boss around me and @wbderry.bsky.social). jobs.sciencecareers.org/job/673968/p...
- Reposted by André DiasCatch up on Development presents… July webinar on early embryogenesis Featuring talks from @lakshmib02.bsky.social, @dias-andre.bsky.social and @nikhil-mishra.bsky.social 🎥 thenode.biologists.com/catch-up-on-... @dev-journal.bsky.social #DevBio
- Tune in tomorrow if you are interested in understanding how stem cells can be used to make different parts of our body
- Sign up to attend our next Development presents... webinar on early #embryogenesis, featuring talks from @lakshmib02.bsky.social, @dias-andre.bsky.social and @nikhil-mishra.bsky.social 📅Wed 9 July 15:00BST (UTC+1) Register here: us02web.zoom.us/webinar/regi... #DevBio @dev-journal.bsky.social
- Reposted by André DiasSign up to attend our next Development presents... webinar on early #embryogenesis, featuring talks from @lakshmib02.bsky.social, @dias-andre.bsky.social and @nikhil-mishra.bsky.social. 📅Wed 9 July 15:00BST (UTC+1) Register here: us02web.zoom.us/webinar/regi... #DevBio @dev-journal.bsky.social
- Reposted by André DiasIn which we discuss the homologies between amphibian and mammalian organizers from the perspective of #gastruloids with special relevance to recently described A and C gastruloids as containing Spemann/Mangold and Trunk/Tail organizers www.sciencedirect.com/science/arti...
- Reposted by André DiasExperimental embryology postdoc available in my lab at the @biology.ox.ac.uk @ox.ac.uk working on the evolution of vertebral counts. Reach out if you’re passionate about EvoDevo, enjoy lab work and microscopy and are into or could get into cichlid fishes. Deadline on the 16th June. Please share!
- We've just updated our manuscript to a more 'publishable' version! www.biorxiv.org/content/10.1... New details about the role of Wnt in suppressing neural differentiation and fostering a posterior epiblast state, and the temporal effect of Nodal signalling in driving mesendodermal fates
- www.biorxiv.org/content/10.1... Here we explore the role of #Wnt and #Nodal signalling during mammalian gastrulation using #gastruloids. Building on the work of many labs, we propose that antagonistic signalling-dependent #modularity in the PS establishes the early mammalian body plan.
- Great work from Alexandra and Sebastian et al showing how gastrulation is governed downstream of Wnt and Nodal. Two competing transcriptional modules - two opposing signalling activities - orchestrate the emergence of the mammalian body plan. moving forward, together
- Two transcriptional modules that control mammalian #gastrulation that are functionally linked through their GRNs www.biorxiv.org/content/10.1... and paced by interactions between Wnt and Nodal signalling Great collaboration with S Arnold and K McDole's labs #gastruloids
- Reposted by André DiasDifficult to believe that such a community has emerged @ #gastruloids as a model system to explore many aspects of #DevBio. Great to see a room so full of people, curiosity and good Science @prbb.org @upf.edu Thank you to all that have made this possible & of course to the participants
- Reposted by André DiasThere's increasing evidence that in organoid/embryoids conditions of cells at start of experiments is crucial/ determines outcome. Much to be learnt still. Taking advantage of mouse #gastruloids, two groups explore this here. Important work to calibrate the field www.biorxiv.org/content/10.1...
- Reposted by André DiasN2B27 media formulations influence gastruloid development biorxiv.org/content/10.1101/202…
- Fun collaboration! All the nitty-gritty about N2B27 and gastruloids. Kudos to all the authors, particularly Tina Balayo (¡que va de primero!)
New Gastruloid preprint just landed... nice collaboration between our lab, @dias-andre.bsky.social, and @amartinezarias.bsky.social www.biorxiv.org/content/10.1...
- Reposted by André Dias🧫Looking for a PhD to start Autumn 2025? We're recruiting! 🧪 The project will focus on using #embryomodels to explore #development & could cover a range of specific questions. Please RT! 🙏 Apply via the portal, and get more details here: www.crick.ac.uk/careers-stud...
- Reposted by André DiasThe Lanner lab is recruiting a postdoctoral fellow to continue developing our strategy to generate pluripotent stem cell derived photoreceptors for treatment of blindness. Looking for talented colleague to join our team. @ki.se ki.varbi.com/what:job/job...
- Reposted by André DiasWe are looking for a new Executive Editor on the journal, with @katherine-brown.bsky.social taking on a new role at @biologists.bsky.social. If you're an experienced editor with a love of developmental biology and its community, this could be the job for you. Full details in the link below.
- Reposted by André DiasI am recruiting an #ERC funded PostDoc to work on the evolution of vertebral counts in cichlids. This is an experimental project & will be looking for candidates with experience generating reporter lines, live-imaging and experimental embryology. Application deadline: 25th Feb. tinyurl.com/33jbu8fa
- Reposted by André DiasJob Alert! We are recruiting a postdoc for organoid technology at RIKEN BDR, Japan. This is a valuable opportunity to work in collaboration with multiple labs, aiming for an advanced integration of developmental biology and engineering. Please contact! www.riken.jp/en/careers/r...
- Reposted by André Dias‼️The Cell and Developmental Biology Department at UCL is looking for potential candidates for their Research Career Development Fellowships with a potential for tenure-track‼️ And believe it or not, UK Research Councils are not frozen🤗 Please spread the words! www.nature.com/naturecareer...
- Reposted by André DiasWe are proud to announce the #BaCell3D Science Bridging Program (SBP)! SBP aims to connect #organoid researchers around the globe to the Basel community. We offer financial support to selected applicants who can demonstrate motivation for participation and lack of alternative funding sources ⬇️
- Reposted by André DiasThrilled to share our new preprint from Ye Zhu in the lab. www.biorxiv.org/content/10.1... . We look at the cell fate potential and degree of cadherin switching of human ES cells differentiated to different primitive streak coordinates.
- Reposted by André DiasBirth defects are the #1 cause of death in the first year of life (🧵). Birth defects kill more than twice as many children as cancer. Birth defects are diseases of developmental biology. Here are CDC statistics for 2021. 1/5 wisqars.cdc.gov/pdfs/leading...
- Reposted by André Dias📣 Please share: We’re hiring a tenure-track Group Leader in Multicellular Systems to explore the molecular and cellular mechanisms driving the formation, maintenance, or destabilization of tissues, organs and organisms. Apply at: www.fmi.ch/education-ca...
- Reposted by André DiasAnnouncing this upcoming conference: GASTRULATION RELOADED: Developing, engineering, and evolving the body plan Join us as we explore the latest research on gastrulation and axis formation/elongation, featuring common, exotic, and synthetic embryos! 📅 14–17 October 2025 📍 Paris, France
- Reposted by André Dias1/3 Embryogenesis requires fit cells. Here, following work from @miguel-torres-1963.bsky.social & @tristanrodriguez72.bsky.social and led by @joshifrenster.bsky.social we develop a #gastruloid model of #CellCompetition www.biorxiv.org/content/10.1... showing it recapitulates much of the embryo 🧵
- Reposted by André DiasPostdoc recruitment for an ERC-funded project! Are you eager to resolve embryonic cell fates with next generation single cell linege tracing? We use in utero barcoding & omics to map development, providing a basis for high throughput perturbations.. Pls re-post! Apply: ki.varbi.com/en/what:job/...
- Reposted by André DiasP.S. for some scientific content, check out this 'behind the paper' post I wrote for @the-node.bsky.social describing the background and origin story of our recent study using signal-recording genetic circuits to decode gastruloid symmetry breaking! thenode.biologists.com/behind-the-p...
- Reposted by André DiasFor some time now we’ve been aware that Chiron #gastruloids, while representing well axial elongation, exhibit a shortage of anterior fates. Here www.biorxiv.org/content/10.1... @Dias and colleagues uncover the reason and explain the implications for our understanding of mammalian gastrulation 🧵
