Daphna Nachmani
Cell identity, RNA modifications and blood (with a soft spot for herpesviruses). PI @HebrewU. nachmanilab.com
- Excited to share our new paper in Blood @bloodjournals.hematology.org! 🎉🧬 doi.org/10.1182/bloo... We reveal that dynamics of ribosome composition control translation across the hematopoietic hierarchy and are essential for hematopoietic stem cell fitness🔬🩸
- Using ultra-low input Ribo-seq, we show that translation capacity distinguishes discrete cell types and defines hematopoietic differentiation trajectories. Integrating this with ultra-low input rRNA 2’-O-methylation profiling, we uncover progressive methylation dynamics
