Daniel Drucker
A clinician scientist at LTRI @sinaihealth studying Glucagon, GIP, GLP-1, GLP-2, diabetes, obesity, metabolism and the gut endocrine system
- Making gut epithelium, an update from the maestro @HansClevers www.cell.com/cell/fulltex... #stemcells @cellcellpress.bsky.social
- Here the authors highlight the therapeutic potential of a ketogenic diet and microbiome modulation for the treatment of sepsis. www.cell.com/cell-metabol...
- Studies in cells and mice reveal that the human GLP1R A316T variant exhibits characteristics of constitutive activation but dampened GLP-1RA responses www.science.org/doi/10.1126/...
- Expanding evidence that the brain controls peripheral immune responses. A bidirectional tumour–brain communication network involving Npy2r vagal sensory input and sympathetic output that cooperatively regulate anti-cancer immunity www.nature.com/articles/s41...
- As the #obesity #weightloss medicine market matures, @novonordisk looks to the pipeline including the unimolecular Amycretin entering P3 trials #TD assets.main.pro2.maf.media-server.com/da6ae6453818...
- As the orforglipron clinical trials portfolio expands #weightloss #T2D #obesity #CVD two notable trials in cardiovascular disease and peripheral artery disease are now highlighted investor.lilly.com/static-files...
- Health care registry data from Ontario with 10 yr F/U reveals that maternal #diabetes particularly #T1D and #T2D is associated with a small increased epilepsy risk in offspring publications.aap.org/pediatrics/a...
- A new look at the development of ILC lineages with perspectives on links to NK and T cells #inflammation www.nature.com/articles/s41...
- Alcohol use disorders and use of GLP-1 medicines after bariatric surgery. A real world perspective jamanetwork.com/journals/jam...
- Dissecting the importance of the murine GCGR vs the GLP-1R for the CNS and #weightloss actions of survodutide @MolMetab www.sciencedirect.com/science/arti...
