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@cp-cellmetabolism.bsky.social: Mice retained normal muscle function and health even though their NAD+ levels were reduced by 85%. Given that NAD levels drop by only up to 30% through ageing, the findings challenge the health benefits claimed by supplement companies.
www.cell.com/cell-metabol...
NAD depletion in skeletal muscle does not compromise muscle function or accelerate aging
NAD depletion in skeletal muscle does not impair tissue integrity and function or
accelerate aging, as shown in a mouse model with an 85% decrease in muscle NAD+ levels.
Muscle structure, metabolism, ...
