Carolina Sanchez-Rocha
Postdoc at @Weizmann Institute in Naama Barkai's lab 🧪🧬 | Structural biologist | Evolutionary biologist 🌳🪸🦠 | Art lover 🎨
- Reposted by Carolina Sanchez-RochaThe next ProSE Seminar will be given by Joana Pereira @joanampereira.bsky.social (VIB, KU Leuven) 🗓️ November 11th, 5pm CET Registration is now open: tinyurl.com/prose-seminar2 Please share!
- Reposted by Carolina Sanchez-RochaThe next Protein Structure Evolution Seminar will be given by Stephen Fried (JHU): Title: “Who Cares About Protein Refolding Anyway?: Why Some Microbes Do and Others Don’t” Date: October 14th, 5 pm CET Registration link: tinyurl.com/prose-seminar2
- Reposted by Carolina Sanchez-RochaHappy to share Piecing Together the History of Protein Folds From a Fragmented Evolutionary Record 🧪 It appears as part of a Special Section in @genomebiolevol.bsky.social organized by @cpuentelelievre.bsky.social @proteinmechanic.bsky.social and J. Douglas doi.org/10.1093/gbe/...
- Reposted by Carolina Sanchez-RochaHow does catalysis emerge from non-catalytic domains? In our new paper, we show that catalytic activity can arise without conserved active-site residues — through multimerization and electrostatic features instead. A striking case of catalysis evolving from binding.
- @claudele.bsky.social et al. studied the fundamental question of how enzymatic activity emerges by focusing on type B dihydrofolate reductases, suggesting DfrB domains evolved rudimentary catalysis from a binding capacity. 🔗 doi.org/10.1093/molbev/msaf215 #evobio #molbio
- 🌍ProSE Online Talk 📅 Tue Sep 9 | 🕔 5pm CET How does protein sequence → structure → function really work? Prof. Nir Ben-Tal will show how AI (CLSS) is reshaping our view of the protein universe and uncovering hidden evolutionary design. 🚀 Don’t miss this! Registration: tinyurl.com/prose-seminar2
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- 🚨 Unravel BILLIONS of years of protein evolution! 🚨 How did protein structures emerge and evolve over deep time? Join @zachary-ardern in the next ProSE Seminar! 📅 March 11, 3PM GMT 🔗 tinyurl.com/prose-seminar2 #ProteinEvolution #StructuralBiology
- 🧬 New research reveals that encoded & non-genetic protein variants shape the human proteome in ways previously unknown! These **alternative proteoforms** expand protein function bypassing genetic constraints. 🔗 Check it!: www.biorxiv.org/content/10.1... #Proteomics #CentralDogma #Translation
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- New seminar series! Join us to explore how protein structures evolved! Kicking off with the outstanding work of Andrei Lupas, who revealed how ancient peptides gave rise to modern protein folds ⚗️💫 ProSE launches one day before Darwin's day! 📅 Feb 11, 3PM GMT 🔗https://tinyurl.com/prose-seminar1
