✨ Key Contributions: 1️⃣ Perturbation-guided generation: Predicts high-resolution cellular phenotypes in large fields of view. 2️⃣ Generalization: Works with genetic and chemical perturbations, even unseen interventions.

3️⃣ Validation: Tested on 3 public Cell Painting datasets, excelling in fidelity, biological interpretability, and visual quality. 🧬 MorphoDiff bridges the gap between transcriptomic-level tools and rich phenotypic insights from high-content microscopy, driving progress in drug discovery.