New paper by Arpit Swain, José Borghans and Rob de Boer, now in
@plos.org Computational Biology. Using mathematical modeling, they show that estimating cell lifespans from deuterium labelling requires considering turnover rates of precursor cells.
Find it here:
journals.plos.org/ploscompbiol...
How are estimated cellular turnover rates influenced by the dynamics of a source population?
Author summary The expected lifespan of different types of cells is a fundamental biological quantity that is essential to know in order to advance translational medicine, for example, to improve immu...