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@inikon.bsky.social used modular proximity labeling to identify ciliary EV cargo in
#celegans. This EV-TurboID approach can be applied in cell- & tissue-specific manners to define the composition of distinct EV subtypes, a major challenge of the EV field.
www.nature.com/articles/s41...
Polycystins recruit cargo to distinct ciliary extracellular vesicle subtypes in C. elegans - Nature Communications
Decoding the content of extracellular vesicles (EVs) is key to understanding cell communication. Nikonorova et al. used targeted proximity labeling to uncover polycystin EV cargo and cargo-loading mec...