Chromatin labeling and imaging group
MPI for Multidisciplinary Sciences
Fluorescent #probes for live-cell #nanoscopy: #STED, #MINFLUX and #confocal. We do the job, all of you judge if it is useful!
- New Year, New Microscope! We just got upgraded to Abberior MIRAVA POLYSCOPE — confocal → MATRIX → STED. First test looks good, large field-of-view and nice STED images using our probes. @abberior.rocks @stefanhelllabs.bsky.social @mpi-nat.bsky.social #microscopy #livecell #fluorescence #bioimaging
- New preprint! The remarkable stability of proline-derived cofactors opens efficient DNA labeling possibility using methyltransferases even at harsh conditions. www.biorxiv.org/content/10.6... Congratulations to Ruta and Jonas . #Biochemistry #DNA #Fluorescence
- Wish all of You Merry Christmas and a Happy New Year!!! Enjoy AI-generated card for Chromatin labeling and imaging @andimaging.bsky.social
- New preprint! We systematically evaluate red-shifted rhodamine-based DNA probes for in vivo imaging. Congratulations to Kamila and Shalini et al! Job done at @mpi-nat.bsky.social and @imprsgs.bsky.social ! Read more if you want to know which isomer is the best: www.biorxiv.org/content/10.6... .
- 6SiR-C3-NextA is bright far-red, cell-permeable probe for live-cell selective HDAC6 imaging. Congratulations to Van-Thang Nguyen et al. @vanthang.bsky.social from @imprsgs.bsky.social ! Developed at @mpi-nat.bsky.social nat.bsky.social and published on BioRxiv www.biorxiv.org/content/10.6... .
- Celebrating 2nd PhD student of the group! 🎓 Van-Thang Nguyen (@vanthang.bsky.social) from the Chromatin Labeling & Imaging group successfully defended his thesis through the @imprsgs.bsky.social program at @mpi-nat.bsky.social. A smooth and impressive defense — and his paper is coming soon… 👀📄
- We have introduced a new biocompatible sulfonium-based building block for generation of non-cytotoxic covalent fluorescent probes. The proof-of-concept paper is out in Nature Communications: rdcu.be/eUn8F Great job done by @mauvray.bsky.social at @mpi-nat.bsky.social Enjoy reading!
- The updated Team of @andimaging.bsky.social . We will keep you posted with our newest developments.
- Reposted by Chromatin labeling and imaging groupThrilled to share with you our work on covalent probes! By introducing a biocompatible sulfonium-based cleavable linker, we developed a series of fluorescent probes that can label covalently endogenous tubulin in various cell lines. www.biorxiv.org/content/10.1... #Chembio #FluorescenceFriday
