- Takeaways from U.S. POINTER top line results: ➡️ Both a structured & a self-guided intervention improved cognition, with the structured group improving even more. ➡️ Cognitive benefits were consistent across age, sex, ethnicity, heart health status and APOE e4 genotype. bit.ly/USPointerRel... #AAIC25Jul 28, 2025 18:34