Nastia Lyulina
PhD student w/ Benjamin Good and Dmitri Petrov at Stanford University interested in evolutionary dynamics & somatic evolution
alyulina.github.io
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- Reposted by Nastia LyulinaNew preprint to close out the year! Led by Alana Papula and together with Daniel Fisher, we used single-cell genomes to infer the evolution of Prochlorococcus—one of the most abundant and genetically diverse bacteria on Earth. Check it out here: doi.org/10.64898/202...
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- I was supposed to attend before starting grad school, but the pandemic got in the way – if you can go, this would be a great way to explore questions in evolution!
- The 2026 Guarda Summer Course in Evolutionary Biology is now accepting applications. Amazing place, amazing course, amazing opportunity for early grad students. tb.ethz.ch/education/gu...
- Reposted by Nastia LyulinaAllele Frequencies at Recessive Disease Genes are Mainly Determined by Pleiotropic Effects in Heterozygotes biorxiv.org/content/10.64898/20…
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- Reposted by Nastia LyulinaCome and join us here in Cambridge! Applications open for a new faculty position, for a researcher in computational and/or theoretical biology, based jointly in Genetics and Mathematics. Happy to answer questions about research, teaching and working here. www.cam.ac.uk/jobs/faculty...
- How is functional variation at large-effect loci maintained in natural populations, even as environments change? In a paper led by @mkarag.bsky.social, we tracked known pesticide resistant alleles in outdoor 𝘋. 𝘮𝘦𝘭𝘢𝘯𝘰𝘨𝘢𝘴𝘵𝘦𝘳 cages & inferred selection and dominance from temporal sequencing data.
- Simultaneously inferring both parameters is generally difficult, especially for deleterious alleles. In our experiment, however, costly resistant alleles remained low in unexposed cages; in exposed cages, they rose in frequency with pesticide application and began to decline once it was removed.
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- Looking forward to #evolution2025! I will be talking about how time-varying demography and selection shape the site frequency spectrum — Saturday at 4:15 pm, Population Genetics Theory IV. Come say hi if you are around!
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- Reposted by Nastia LyulinaWe are excited to announce a new faculty position here in Cambridge, for researchers in computational and/or theoretical biology, based jointly in Genetics and Mathematics. Come and join us! Happy to answer questions about research, teaching and working here. www.jobs.cam.ac.uk/job/50414/
- Reposted by Nastia LyulinaThis allowed us to visualize the pattern of clones in the tumor! 10/16
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- Happy to have been part of this story!
- Reposted by Nastia LyulinaThis paper has been a long time coming: We looked at the genomes of historical bacterial samples over a century to look for trends of antibiotic resistance genes, finding multiple instances of them in infections before the age of antibiotics, but an increase in both frequency and mobility after
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- How do we predict the statistical associations between mutations that spontaneously emerge in an evolving population? Excited to share some new work w/ @zzzhiru.bsky.social and @benjaminhgood.bsky.social that approaches this question!
