Males and females process pain through different brain pathways. Current pain management has been directed to how males process pain. This might also explain why females suffer more from chronic pain.
pmc.ncbi.nlm.nih.gov/articles/PMC...
Self-regulated analgesia in males but not females is mediated by endogenous opioids
Converging lines of preclinical and clinical research indicate that females, in stark contrast to males, display an increased prevalence of chronic pain. Females also demonstrate weaker analgesic effi...
