Alison Feder: Really excited about this new work from Sam Hart (and joint with @kelleyharris.bsky.social) trying to disentangle mutational differences between groups of cancers. Check out Kelley's thread with the major results!

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Alison Feder alisonfeder.bsky.social
Really excited about this new work from Sam Hart (and joint with @kelleyharris.bsky.social) trying to disentangle mutational differences between groups of cancers. Check out Kelley's thread with the major results!
- Kelley Harris handle.invalid · May 20, 2025
  If you’ve ever wondered about the statistical significance of differences among mutational signature profiles, check out our new Aggregate Mutation Spectrum Distance (AMSD) preprint co-led by Sam Hart and @alisonfeder.bsky.social with @nalcala.bsky.social www.biorxiv.org/cgi/content/...
  A signature-agnostic test for differences between tumor mutation spectra reveals carcinogen and ancestry effects
  
  Mutational signatures contain valuable information about the mutational processes shaping cancer genomes. However, despite dozens of tools to identify signatures in cancer samples, there is not an est...
  
  biorxiv.org
May 20, 2025 20:04
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