Alex Strudwick Young
Asst. Prof. @ UCLA Human Genetics. Statistical geneticist & part of the SSGAC. Mendelian inheritance is the most important natural experiment. alextisyoung.github.io
- Reposted by Alex Strudwick Young[Not loaded yet]
- Reposted by Alex Strudwick YoungPGI Repository v2.0 preprint out! A 🧵 on the main results and updates @robel-alemu.bsky.social @paturley.bsky.social @alextisyoung.bsky.social
- Reposted by Alex Strudwick Young[Not loaded yet]
- Reposted by Alex Strudwick YoungUK Genome Science meeting - Newcastle. 9th - 11th July 2025. Great speakers. Great community. Early bird registration-16th May Abstract submission-23rd May Registration close-26th June If you want that sweet sweet early bird deal - get going quick! www.genomescience.org.uk
- Reposted by Alex Strudwick YoungSome really interesting contrasts in our new "assumption-free heritability" preprint: papers.ssrn.com/sol3/papers....
- Reposted by Alex Strudwick YoungSiblings are not always 50% genetically similar! The difference may vary from 40 to 60%! Our preprint uses this difference via sibling regression to estimate "assumption-free heritability" of socio-cognitive traits /1 @eivindy.bsky.social @rafaelahlskog.bsky.social @renemottus.bsky.social
- Some really interesting contrasts in our new "assumption-free heritability" preprint: papers.ssrn.com/sol3/papers....
- Great work on estimating heritability using sibling relatedness variation (estimated using my software package snipar). Surprisingly low h2 for education and high h2 for IQ (with large SE). Give it a read!
- Siblings are not always 50% genetically similar! The difference may vary from 40 to 60%! Our preprint uses this difference via sibling regression to estimate "assumption-free heritability" of socio-cognitive traits /1 @eivindy.bsky.social @rafaelahlskog.bsky.social @renemottus.bsky.social
- Reposted by Alex Strudwick Young[Not loaded yet]
- Reposted by Alex Strudwick Young[Not loaded yet]
- Reposted by Alex Strudwick Young[Not loaded yet]
- I am recruiting a quantitative/computational postdoc to my group at UCLA. This is a great opportunity to work on foundational theory, methods, and software in statistical genetics. Link to apply: recruit.apo.ucla.edu/JPF10275. Please repost!
- Reposted by Alex Strudwick YoungInstead of listing my publications, as the year draws to an end, I want to shine the spotlight on the commonplace assumption that productivity must always increase. Good research is disruptive and thinking time is central to high quality scholarship and necessary for disruptive research.
- Reposted by Alex Strudwick Young[Not loaded yet]
- Reposted by Alex Strudwick Young[Not loaded yet]
- Reposted by Alex Strudwick Young[Not loaded yet]
- Reposted by Alex Strudwick Young[Not loaded yet]
- Great to see this paper out in Nature today! One aspect that I worked on was the curious result that the education polygenic score predicts neurodevelopmental conditions but this prediction disappears within family.
- 📣 Big news! Our tag-team effort on common variants in rare neurodevelopmental conditions is now out in Nature 📣 Co-first authoring with the brilliant Qinqin Huang🌟—proof that teamwork does make the dream work. 💪 www.nature.com/articles/s41...
- It's possible that this is because the parents' genetics affect the offspring through the env but it could be assortment: parents with lower education polygenic scores based on common variants are more likely to mate with individuals with rare variants that cause neurodevelopmental conditions.
- Reposted by Alex Strudwick Young📣 Big news! Our tag-team effort on common variants in rare neurodevelopmental conditions is now out in Nature 📣 Co-first authoring with the brilliant Qinqin Huang🌟—proof that teamwork does make the dream work. 💪 www.nature.com/articles/s41...
- Reposted by Alex Strudwick Young[Not loaded yet]
- Reposted by Alex Strudwick YoungCheck out this University of Colorado newsletter that describes work being done by IBG faculty member @dangustavson.bsky.social using the VETSA twin dataset to examine genetic and environmental influences on cognitive decline. www.colorado.edu/asmagazine/2...
- Reposted by Alex Strudwick YoungI'm advertising a PhD studentship (open to international students) working on long read pangenome / assembly algorithms in bacteria. Would suit someone with maths/compsci/coding background. Aptitude + interest more important than experience. Details here: www.findaphd.com/phds/project...
- Reposted by Alex Strudwick YoungReview: Inference and applications of ancestral recombination graphs nature.com/articles/s41576-024… (read free: rdcu.be/dVyQH) 🧬🖥️
- Reposted by Alex Strudwick Young[Not loaded yet]
- Reposted by Alex Strudwick Young🚨IBG is hiring for a Tenure Track Assistant Professor! Candidates should have a background in neurogenetics, high-content genomics, experience with iPSC-derived neurons and glia and neural organoids, and expertise in neurodegeneration. More details here: jobs.colorado.edu/jobs/JobDeta...
- Reposted by Alex Strudwick Young[Not loaded yet]
- Reposted by Alex Strudwick YoungOne more week to apply! We are recruiting a postdoc to work on the evolutionary genetics of admixture in maize and teosinte.
- Reposted by Alex Strudwick Young[Not loaded yet]
- The exome sequencing plus imputation pipeline developed by Regeneron is impressive in its efficiency for discovering genetic associations that are potential drug targets. But having whole genomes for the entire UKB is cool and will prove more useful in the long run www.nature.com/articles/s41...
