Alessandra Brambati
Assistant Professor at Anschutz CU | Big fan of molecular mechanisms that govern genome stability | 🇮🇹 to 🇺🇸
Lab Website sites.google.com/view/brambatilab/home
- Life is difficult but @heyzajr.bsky.social you just made my day better. I love it so much, it’s gorgeous
- Reposted by Alessandra BrambatiJoin us next Tuesday, December 2 at 5pm (Rome) / 11am (NYC) for an exciting GIIN webinar featuring @peterlylab.bsky.social and @alebrambati.bsky.social! Zoom link: uniroma1.zoom.us/j/95149984403 Register here to become part of our community: docs.google.com/forms/d/e/1F...
- Reposted by Alessandra BrambatiWe thank Evi Soutoglou and @rubenvanboxtel.bsky.social for sharing their exciting data with the GIIN community yesterday! Our next webinar is on December 2nd, featuring @peterlylab.bsky.social and @alebrambati.bsky.social. Do not miss it! Sign up for updates: docs.google.com/forms/d/e/1F...
- Excited to share our latest from my postdoc at @mskcancercenter.bsky.social in the Sfeir Lab, in collaboration with the Simon Powell Lab! We uncovered a novel genome repair mechanism in human cells: RNA-templated DNA double-strand break repair (RT-DSBR). (1/5)
- Using fluorescent and sequencing-based assays, we show that RNA-containing oligos and even mRNA can serve as templates for DSB repair in human cells. But which enzyme enables this RNA-templated process? (2/5)
- CRISPR/Cas9 screens identified DNA polymerase ζ (Polζ) as essential for RT-DSBR. This translesion polymerase surprisingly acts as a reverse transcriptase—copying RNA into DNA right at break sites. (3/5)
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- Reposted by Alessandra BrambatiExciting seminar series from Genome integrity italian Network (GiiN), chaired by myself and Raffaella Di Micco! Short talks (2x30’), at convenient time for EU/USA attendees. Big shots and raising stars in an expanding field. See flyers + link to receive email alerts. Please repost to your network!👇
- Reposted by Alessandra BrambatiA brilliant Banksy.
