Sdelci Lab
The Epigenetic Face of Cancer Metabolism Lab
We study NUCLEAR METABOLISM at CRG, Barcelona
sdelcilab.crg.eu
- And then our first PhD student wins the award for Best Thesis of the Year… a wonderful Christmas present 🎄✨ It really makes us feel we’re doing things the right way. Congratulations, Dr. Natalia Pardo Lorente, so well deserved 👏🎓 @crg.eu @upf.edu @prbb.org
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- I am (Sara Sdelci, @crg.eu) very happy to have been selected as an @embo.org YIP! Thank you for selecting our project on how nuclear metabolism shapes cellular proliferation and aging; we are truly excited for the beautiful science ahead!
- Congratulations to the new cohort of 28 EMBO Young Investigators! They are joining an international network of more than 800 life scientists – Welcome! Read the press release here: embo.org/press-releases/twen…
- Dr. Jane Goodall has passed away. Her groundbreaking work with chimpanzees and her lifelong dedication to conservation changed how we see and care for our planet.
- Jane Goodall has died at the age of 91. In 2020, Goodall spoke with Science Editor-in-Chief H. Holden Thorp for a #ScienceEditorial reflecting on the 60th anniversary of her arrival in Gombe to study wild chimpanzees. Read more: scim.ag/472Chb8
- Reposted by Sdelci LabHappy to share the Biodiversity Cell Atlas white paper, out today in @nature.com. We look at the possibilities, challenges, and potential impacts of molecularly mapping cells across the tree of life. www.nature.com/articles/s41...
- Reposted by Sdelci LabScience: only when you write up the manuscript, you realize what you should have done.
- Being open to new ideas: Metabolic Enzymes in the Nucleus as Chromatin Instructors? Merging #chromatin #epigenetics #metabolism To understand new cellular rules.
- 🚀 We’re excited to share our latest publication in collaboration with Verena Ruprecht's group at @crg.eu Mechanobiology meets Nuclear Metabolism www.nature.com/articles/s41...
- Uncovering how mechanical forces can influence nuclear ATP levels, with downstream effects on DNA damage response and cell cycle progression. #Mechanobiology #NuclearMetabolism #CellFate #DNArepair #CellCycle
- Fantastic to see this wonderful piece out! Happy to have contributed to this effort 💪
- Very excited that our work describing hu.MAP3.0 is published in @molsystbiol.org. Here we use machine learning to integrate >25k mass spectrometry experiments to place ~70% of human proteins into 15k protein complexes. www.embopress.org/doi/full/10....
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- As promised, here is our NEW preprint on CELL CYCLE ASSOCIATED PIP2 NUCLEAR METABOLISM by our SUPER postdoc Toni Gañez, who knows all the secrets of FUCCI reporters 👇 www.biorxiv.org/content/10.1...
- Our initial question was: does the cell cycle control the association of metabolic enzymes with chromatin? The short answer is YES! We adapted the FUCCI system and extensively characterized U2OS FUCCI using HT-microscopy and FACS.
- 1) By integrating FUCCI reporters and classical proliferation/senescent markers, we identified a population of cells, which we termed G0-senescent, that had never before been identified using FUCCI.
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View full threadBIG THANKS to everyone involved, especially Toni for his amazing work! Thanks to our sponsors: @ageinves.bsky.social @ERC_Research #ERCStG EPICAMENTE @crg.eu
- Merry Christmas from the Sdelci Lab! Stay tuned for our last preprint before the end of the year... lots of FUCCI colors 🎄-style and metabolic enzymes on chromatin during cell cycle progression COMING SOON 💥
- Reposted by Sdelci Lab🚀 The NUCLEAR Project website is live! 🌟 Explore how metabolism regulates genome function & cell identity. 💡 Cutting-edge research, interdisciplinary training, & international collaboration. 🌍 Learn more: nuclear-dn.eu #MarieCurieActions #PhD
- Reposted by Sdelci Lab🚨 16 PhD positions open in early 2025! 🚀 Join NUCLEAR for cutting-edge research on nuclear metabolism, cell identity, and genome function. 🌍 Details on projects, eligibility & applications coming soon.Stay tuned! #PhDOpportunities#MarieCurieActions 👉http://nuclear-dn.eu
- Looking for a PhD position? We have 16 available in our NUCLEAR Horizon MCSA Doctoral Network. Don't miss the opportunity! nuclear-dn.eu/2024/12/18/1...
- We made it among the BEST PICTURES OF THE YEAR by @natureportfolio.bsky.social www.nature.com/immersive/d4... Beautiful image representing in red the nuclear localization of MTHFD2 in pluripotent colon organoids by @NataliaPardoL Find the manuscript here: www.nature.com/articles/s41...
- Thanks to @bpodaily.bsky.social for choosing our beautiful colon organoid as a picture of the day. MTHFD2 in the nucleus in red: bpod.org.uk
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- Reposted by Sdelci Labhey everyone! i made a list of some useful starter packs (primarily biology/earth sciences with a few bonus things thrown in) to share with friends who have joined bsky in the last week and thought it may be useful for some people here too! 🌍🧪 #SciSky #BioSky docs.google.com/document/d/1...
- Reposted by Sdelci LabI have curated a second "metabolism" starter pack, as the first quickly got full. Please have a look, and I am happy to add others (sorry for those who may appear in both): go.bsky.app/CH1MctZat://did:plc:mklo35zasunpbla4ipbtfafk/app.bsky.graph.starterpack/3lbwxfjr2f72n
- Amazing opportunity to join a great group.
- We have two open PhD positions in my group at @crg.eu. We are seeking candidates with a background in computational and/or molecular biology, and with a broad interest in evolutionary biology, gene regulation, and comparative genomics. 📅Apply before January 12 here: www.crg.eu/en/content/t...
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