Matt Harkey, PhD
🦵 Researching why patients after knee injury are at 📈risk for arthritis 🧪
🔎 Early OA Detection •🩻 Ultrasound Imaging •⚙️ Biomechanics
Assistant Professor • Michigan State University 🏛️
Director • Athletic Injuries & Rehabilitation (AIR) Labs
- What. A. Day.💥 🦴The inaugural @henryfordhealth.bsky.social + @michiganstateu.bsky.social Musculoskeletal Research Retreat was an incredible success! 🤝~90 attendees from both institutions came together to build connections, share ideas, and spark collaboration. ➡️https://lnkd.in/eGK6VqNj
- I was nervous planning it—would anyone show up or engage? But it turned into one of the most inspiring days I’ve been a part of. Packed sessions, amazing speakers, and real momentum for future partnerships across clinical and academic teams at HFH + MSU. ⚡️

- 🙏 Thank you to: 🎤 Our bold, visionary speakers 🧠 Our engaged poster presenters 🤝 Everyone who showed up and leaned into the discussion
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View full threadAnd huge thanks to the HFH + MSU Health Sciences partnership for Affinity Group funding 💼 This retreat is proof of what’s possible when you invest in collaboration. Let’s keep the momentum going! 🚀
- Pumped to see our team’s work on early inflammatory changes following knee surgery take center stage at #ACSM25 today! 🧠🗣️🔥 We’re showcasing how ultrasound gives us a clearer view into joint health and recovery after ACLR. 🔬🦵📈 Just getting started 💪📊 #OA #sportsmed #ACLR #ultrasound
- Reposted by Matt Harkey, PhDExcited to attend the American College of Sports Medicine #ACSM25 meeting in Atlanta this week! Meet us at Booth 802 and check out how our new #pedar with lightweight #plidar technology can help advance your #sports and #biomechanics applications! For more information, visit www.novelusa.com/pedar
- 🚨 Now recruiting 2 PhD students @ MSU! Join a funded study investigating early arthritis after knee surgery using: – 🖥️ Ultrasound imaging – 🦵 Movement biomechanics – 🧠 Psychological & hormonal factors 📍: East Lansing, MI 📩: harkeym1@msu.edu | hartharv@msu.edu 📸 Flyer below 👇
- Reposted by Matt Harkey, PhDExcited to share our work on the small but mighty microRNA-126-3p in @naturecomms.bsky.social! We found this microRNA is elevated in four knee osteoarthritis cohorts and show in an animal model that it reduces the severity of knee osteoarthritis - at least in part via angiogenesis. rdcu.be/ebycj
- 📢 New research challenges BMI as a predictor of ACL recovery. Instead, body composition—lean vs. fat mass—better correlates with strength & function. 🔬 DXA showed: ✅ More lean mass → Stronger quads, better mobility ❌ More fat mass → Worse knee pain & performance 📉 BMI? No significant correlation.
- 💡 Key takeaway: ACL rehab should focus on body composition, not BMI, to optimize long-term outcomes. 📊 Lean mass = strength & function ⚠️ Fat mass = pain & worse performance 📖 Study: pubmed.ncbi.nlm.nih.gov/39929144/
- 📢 Interesting study in Orthopaedic Journal of Sports Medicine 🦵🔬: Among 16,935 pediatric ACL reconstructions, 1.6% developed PTOA within 5 years. Key risk factors: ⚠️ Motion restoration surgery (OR = 5.0) 👶 Age ≤12 (OR = 4.8) ⏳ Delayed ACLR (OR = 1.8) ⚖️ Obesity (OR = 1.4) ⚡ Male sex (OR = 1.3)
- 🦵 ACLR restores stability, but timing & rehab matter! ⏳⚕️ Early surgery (<3 months) and reducing arthrofibrosis may lower PTOA risk in young athletes. 🏹 Further research is needed to optimize long-term joint health. 🔗 pubmed.ncbi.nlm.nih.gov/39926589/
- 🚨 NIH funding is at risk! 🚨 📢 Indirect cost rate changes could slow down life-saving medical research that patients depend on! ❤️🔬🧪 @aimbe-official made it easy to take action! 📩 Send a letter to Congress in under 1 minute! ⏳🏛️ 🔗 Act now: aimbe.org/advocate/wri… 📢 Spread the word! #ScienceMatters
- AIMBE has developed a new advocacy letter on the changes to NIH indirect cost rates: aimbe.org/advocate/wri... We urge the broader biomedical research community to customize this letter (<1 minute) to contact your congressional representatives about the severe consequences of this new policy 👇
- Reposted by Matt Harkey, PhDThanks for this. I linked this thread in my Substack and made a script for people to use to contact their reps! fromthescienceclass.substack.com/p/biomedical...
- 🚨 NIH’s indirect cost policy might not stick. 🧪 Turns out, there’s already a law preventing NIH from making these changes without congressional approval. Hopefully there’s a good chance this IDC change won’t move forward as planned. Something to watch! 👀

- On changes to #NIH indirect rates, there is a law in place that prohibits NIH from making such changes without the approval of Congress. See Division D, Title II Section 224 of The Further Consolidated Appropriations Act, 2024 (Public Law No: 118-47) grants.nih.gov/grants/guide...
- 🔬 NIH’s new policy to cap indirect costs at 15% is a major blow to research institutions. 🧪 💰 Less funding for operations = fewer resources for science. ⚠️ Small institutions may struggle to sustain research. 🏛️ This could impact the future of NIH-funded projects. 🔗 grants.nih.gov/grants/guide...
- 🏆 Wireless ultrasound is a game-changer! 🔬 Our new study in Osteoarthritis Imaging confirms that Clarius wireless ultrasound probes accurately measure knee cartilage thickness—comparable to traditional systems. 📊 A big step toward more accessible ultrasound technology! 🔗: doi.org/10.1016/j.os...
- Can you improve this?? ✅While wireless and traditional ultrasound showed high reliability for cartilage thickness, ❌low reliability for echo-intensity persisted, even after pixel normalization.😕 ⚡This points to room for improvement in ultrasound tech! 📷Examples across scanners & normalization
- Reposted by Matt Harkey, PhDExcited to share the first paper from my PhD in @kelseyhcollins.bsky.social lab where we show that IPFP images using MRI are related to pain and are different with age, obesity and sex. Collab with Richard Souza, Laura Chen, and Emma Nedley. onlinelibrary.wiley.com/doi/10.1002/...
- 🦋 Hello from AIR Labs! 🧪 We study how movement impacts knee OA after injury. Our research focuses on: 🏋️♂️ Biomechanics 🏃 Physical Activity 🩻 Structural Changes 📊 Early Symptoms 👍Our goal? Early detection & prevention of OA. 😁Excited to share & connect! #Ultrasound #Osteoarthritis #ACL #KneeHealth
- Reposted by Matt Harkey, PhDI have started an Orthopaedic Research Starter Pack! Link: go.bsky.app/61hCir6. I am happy to add people -- comment below to be added!at://did:plc:izsprnjy7uvlx2pfupyg42m6/app.bsky.graph.starterpack/3lbb7dvw7rd24