Marcus Böhme
#Microbiota-#Gut-#Brain-Axis | from Early Life to #Aging | Neuroscientist & Nutrition | Working in R&D | Musician | PhD @uniklinik_jena | formerly @Pharmabiotic #cryanlab
📄 scholar.google.de/citations?user=SqMB…
- Reposted by Marcus BöhmeIntroducing Foli-seq in @natbiotech.nature.com today. Foli-seq can be used to measure gut-derived RNA from fecal matter (signals of immune, secretory & epithelial cells). We used this to map gut inflammation, drug response, and host-microbe interactions. 💩🧬💊🦠 www.nature.com/articles/s41...
- Reposted by Marcus Böhme🚨I am looking for a POSTDOC, LAB MANAGER/TECH and GRAD STUDENTS to join my new lab in beautiful Madison, WI. We study how our brains perceive and represent the physical world around us using behavioral, computational, and neuroimaging methods. paulunlab.psych.wisc.edu #VisionScience #NeuroSkyence
- Reposted by Marcus BöhmeAnother review from my lab out this week, on analyzing gut microbiome data from global populations -- tackling computational challenges and providing practical frameworks and resources for the field With Sabrina Arif, @richabdill.com, @samanthagraham.bsky.social www.cell.com/trends/micro...
- Reposted by Marcus BöhmeMetabolic ecology of microbiomes: Nutrient competition, host benefits, and community engineering Review by Erik Bakkeren, Vit Piskovsky, and Kevin R. Foster www.cell.com/cell-host-mi...
- Reposted by Marcus Böhme📈With obesity and overweight expected to affect 50% of the global population by 2035, the need for change has never been clearer. Join experts on 5 June at #EUParliament for an in-depth discussion on tackling this growing health crisis. Register now: bit.ly/3EIlu1H
- Reposted by Marcus BöhmeExcited to share our new work demonstrating a role for astrocytic inflammasome signaling in modulating hippocampal plasticity. @cp-immunity.bsky.social All credit to Kristine Zengeler, who was the brains🧠 and muscle💪 behind this project and is a wonderful collaborator. www.cell.com/immunity/ful...
- Reposted by Marcus BöhmeLots of recent papers discuss the nucleus of the solitary tract in interoception. In this review, we take a sensory processing perspective on how interoceptive signals are encoded in the NTS: www.sciencedirect.com/science/arti...
- Reposted by Marcus BöhmeNEWS&VIEWS | LO Dragsted, @hroager.bsky.social , @catalinacuparencu.bsky.social (U Copenhagen): A methodology for assessing dietary intake using stool metagenomes to detect food DNA🧬💩 bit.ly/4lfJ1aK ?utm_source=bluesky&utm_medium=social&utm_campaign=natmetab
- Reposted by Marcus BöhmeA map of neural signals and circuits traces the logic of brain computation www.nature.com/articles/d41...
- Reposted by Marcus BöhmeInflammatory and anti-inflammatory cytokines bidirectionally modulate amygdala circuits regulating anxiety: @cellpress.bsky.social www.cell.com/cell/fulltex...
- Reposted by Marcus BöhmeIn people with diabetes, GLP-1 and SGLT2i drugs were associated with less Alzheimer's disease and related dementias jamanetwork.com/journals/jam...
- I am excited to share our latest publication where we investigated the impact of a #Bifidobacterium longum strain on #perinatal anxiety and depressive symptoms #mood #stress #postpartum #gutbrainaxis www.nature.com/articles/s41...
- Reposted by Marcus BöhmeThe gut microbiome's link with multiple sclerosis www.cell.com/cell-reports...
- Reposted by Marcus BöhmeDelighted our study (7+ years in the making) is out today in Nature. In a nutshell, 48 hours of antibiotics in week 1 led to impaired vaccine responses up to 15 months later in infants. We show (in-vivo) a probiotic can fix it #microbiome #science #immunology www.nature.com/articles/s41...
- Reposted by Marcus BöhmeSingapore study of 184 women found that daily probiotic Bifidobacterium longum NCC3001 during late pregnancy and postpartum did not ease anxiety or depression symptoms. Results varied widely, suggesting more research is needed. www.nature.com/articles/s41...
- Reposted by Marcus BöhmeCurious about the gut microbiome & its impacts on sleep throughout the adult lifespan? 🦠😴 You're in luck! @isbscience.org PhD student Jacob Cavon led a review of this topic for the @amiposts.bsky.social journal Letters in Applied Microbiology (just accepted): academic.oup.com/lambio/advan...
- Reposted by Marcus BöhmeI received a heartbreaking email today: A paper in a special issue I’m editing is being retracted because one of its authors is afraid of losing their job and their legal status in the U.S. if they publish a scientific study on evolution. Yes, on evolution, nature's engine of diversity.
- Reposted by Marcus BöhmeIn this week’s @nature.com, we publish a group effort to outline a framework for studies with neural #organoids, #assembloids and transplantation. More details below 1/n
- Prohormone cleavage prediction uncovers a non-incretin anti-obesity peptide www.nature.com/articles/s41...
- Reposted by Marcus BöhmeThis administration is destroying US science. "Foreign scientists hired under Title 42 have even more reason to worry... their visas require they leave the country within 60 days unless they obtain a new position. Many have put down roots, bought houses & have children in school."
- Reposted by Marcus BöhmeWhat is your pace of aging? A new @nature.com feature on molecular clocks by gets into the issues surrounding these tests (can is really can't) nature.com/articles/d41... by @heidiledford.bsky.social
- Reposted by Marcus BöhmeGreat minds… within 24 hrs both us at @nature.com and @science.org make similar appeals to the research community. And @holdenthorp.bsky.social and I didn’t even exchange notes about it ;-) 🧪 www.nature.com/articles/d41... www.science.org/doi/10.1126/...
- Reposted by Marcus BöhmeAlmost all grant-review meetings under Trump 2.0 remain suspended at the US National Institutes of Health (NIH), preventing the world’s largest public funder of biomedical research from spending much of its US$47 billion annual budget. go.nature.com/4gM6oW4
- Reposted by Marcus BöhmeMy brother is a wild-land forest fire fighter. He wasn’t fired, but he says that the degraded workforce will struggle to function in the next fire season. These are the heroes who risk everything to save lives and homes.
- Reposted by Marcus BöhmeInterested in doing a PhD in Austria focused on understanding how to engineer the composition of the gut microbiota? Want to work with a brilliant computational biologist and microbiome researcher? See below!
- Hi, we have an open PhD position in our lab starting winter 2025. Join the great MolMed PhD program at a vibrant research institution and help us understand probiotic engraftment. More info at www.dienerlab.com/posts/phd2025/ . Application through the MedUni portal: phd-recruiting.medunigraz.at
- Reposted by Marcus BöhmeA new way to measure your food intake, from your 💩 www.nature.com/articles/s42... www.nature.com/articles/s42... "proof-of-concept for detailed tracking of individual-specific, health-relevant dietary patterns without the need for questionnaires."
- Reposted by Marcus BöhmeJust to add to the impossibility of doing a fully double blind randomized trial for a communicable desease, the placebo group would need to be tested in a population that is not significantly protected by herd immunity to see the effect if the general population stops taking the vaccine. Where??
- Reposted by Marcus BöhmeIntroducing "Metagenomic Estimation of Dietary Intake", or "MEDI": a data-driven approach to estimating dietary and nutritional intake from stool DNA 💩 - 🍌🥦🐟🥩📈 See @cdiener.com's excellent thread below. We are really proud of this work, and we hope it is useful to the scientific community.
- Happy to announce that MEDI, our method to quantify dietary intake through metagenomics is out now. 🧬 🧪🧫🦠 www.nature.com/articles/s42... #metagenomics #microbiome #microbiomesky So what is MEDI? A combination of two things:
- Reposted by Marcus BöhmeIf this sticks, it will destroy academic science in the US, and it will stifle technological innovation and economic growth. It cannot stand. Contact your representatives and senators.
- Reposted by Marcus BöhmeOur study @cellpress.bsky.social finds healthy Canadians that consume a non-industrialized-type #diet can modulate their #microbiome, boost beneficial metabolites and improve their health. In just 3 weeks: LDL cholesterol ↓17% fasting glucose ↓6% CRP ↓ 14% www.cell.com/cell/fulltex...
- Reposted by Marcus BöhmeDelighted to highlight new work by Kelly Jameson and colleagues showing that select microbial metabolites in the small intestinal lumen regulate vagal activity www.cell.com/iscience/ful...
- A comprehensive spatio-cellular map of the human hypothalamus | John A Tadross, Lukas Steuernagel, Georgina K.C. Dowsett et al. @gilesyeo.bsky.social & MPI Metabolism www.nature.com/articles/s41...
- Reposted by Marcus BöhmeDiscovery of 22 proteins associated with healthy aging, protection from cardiometabolic disease, and their influence by the gut microbiome www.nature.com/articles/s42...
- Reposted by Marcus Böhme[Not loaded yet]
- Reposted by Marcus BöhmeNEW COMMENT: Microbiome science needs more microbiologists @abaumler.bsky.social and Lauren Radlinski argue that integrating microbiologists and fundamental microbiological concepts should help advance microbiome science www.nature.com/articles/s41...
- Reposted by Marcus BöhmeA great opportunity to start your own research group @pasteur.fr in Developmental Biology👇 research.pasteur.fr/fr/call/call...
- Reposted by Marcus BöhmeReally proud to start the year by sharing our new review in @endosocjournals.bsky.social on the roles of GLP-1 in eating and obesity treatment, led by superstar postdoc @laurenjonesucl.bsky.social! academic.oup.com/endo/article... 🧪🧠📈 #neuroscience #neuroskyence #GLP-1 #obesity #wegovy #ozempic
- Reposted by Marcus BöhmeSuper proud of this paper on infant gut microbiome age coming from my lab. The paper has just been published with @springernature.bsky.social in @naturecomms.bsky.social. Read about it here: rdcu.be/d6cCw.
- Reposted by Marcus BöhmeCould gut bacteria be the reason behind your sugar cravings? 🤤 Check out this new paper by Zhang et al. linking a gut microbe, a free fatty acid receptor, and sugar intake. www.nature.com/articles/s41...
- Reposted by Marcus BöhmeInteresting new paper -- evolutionary adaptations in Bifidobacterium across a huge range of host species www.biorxiv.org/content/10.1...
- Reposted by Marcus BöhmeDelighted to share the first peer-reviewed paper from our team @camvetschool.bsky.social where we investigate the ecological dynamics of Enterobacteriaceae in the human gut #microbiome: www.nature.com/articles/s41... @naturemicrobiol.bsky.social
- Reposted by Marcus BöhmeHost metabolism balances microbial regulation of bile acid signalling | @nature.com www.nature.com/articles/s41...
- Reposted by Marcus BöhmeNew PERSPECTIVE - A decade of advances in human gut microbiome-derived biotherapeutics by Alena Pribyl, Phil Hugenholtz & Matthew Cooper www.nature.com/articles/s41...
- Reposted by Marcus BöhmeI’m excited to share my latest paper @cp-cellmetabolism.bsky.social. HakanK and I recorded from AgRP neurons continuously for 1 month and found some exciting things during ad lib feeding, fasting and on circadian timescales www.cell.com/cell-metabol....
- Reposted by Marcus BöhmeThe costs and benefits of a dynamic host microbiome www.cell.com/trends/ecolo...
- Reposted by Marcus BöhmeThe scientist who is responsible for driving GLP-1 drugs for the treatment of obesity and testing them for prevention of Alzheimer's disease—Lotte Bjerre Knudsen— tells her story in a remarkable conversation. Full transcript, or video, all free, no ads. erictopol.substack.com/p/lotte-bjer...
- Reposted by Marcus BöhmeI thought it could be nice to connect the community of researchers exploring body-brain interactions on bsky, so here is the Body-Brain Interactions Starter Pack! 🫀🫁👀🧠 #neuroskyence #academicsky Let me know if you would like to be added or know someone to add. Enjoy and share! go.bsky.app/Fwqeu32at://did:plc:ocrnjyhkregsz3ez46svw3yy/app.bsky.graph.starterpack/3l4wgy6vfb225
- Reposted by Marcus BöhmeReally pleased to see reviews like this, expanding on our discoveries that #cerebrovascular dysregulation during development contributes to autism spectrum disorders. physoc.onlinelibrary.wiley.com/doi/10.1113/...
- Reposted by Marcus BöhmePeople sometimes make fun of science that sounds stupid and random. Meanwhile, a study of lizard saliva turned into a peptide medication, which was turned into a diabetes medication, which was turned into a GLP1 weight loss drug, that just became the first therapy every approved for … sleep apnea
- Reposted by Marcus Böhme…And if you want to know more about BAMs in particular and their roles in shaping 🧠 function in health and disease read this one written by Rejane Rua and me: www.cell.com/trends/immun...
- Effects of Aging on Diurnal Transcriptome Change in the Mouse Corpus Callosum @cp-iscience.bsky.social www.cell.com/iscience/ful...
- Chronological versus immunological aging: Immune rejuvenation to arrest cognitive decline www.cell.com/neuron/abstr...
- Reposted by Marcus BöhmeDo you want to start a PhD and study the transmission of the microbiome and alterations in neurological disorders? 🦠🖥️ We have a fully-funded position (deadline: 05/01/25)! All details: tinyurl.com/2b3sre8a Feel free to get in touch for more info!
- Response of the gut microbiome and metabolome to dietary fiber in healthy dogs | Amrisha Bhosle, Matthew I. Jackson, Aaron Walsh, Eric A. Franzosa, Dayakar V. Badri, Curtis Huttenhower journals.asm.org/doi/10.1128/...
- Reposted by Marcus Böhme"Why does the brain need billions of neurons to process 10 bits/second? Why can we only think about one thing at a time?" www.cell.com/neuron/fullt... From The Unbearable Slowness of Being
- Reposted by Marcus BöhmeMove over mitochondria, a new organelle called the nitroplast is here. In a Science study from earlier this year, researchers report that a nitrogen-fixing organelle has been identified in a marine alga. Learn more in this #SciencePerspective:
