Jeremy Elman
Alzheimer's & aging researcher at UC San Diego
- Reposted by Jeremy ElmanThe extended version of my thesis procrastination project/subcortex visualization package is out now in both Python and R, now that I’ve graduated 🤠 This figure shows the 9 atlases included (and counting)! Preprint: www.biorxiv.org/content/10.6... Website: anniegbryant.github.io/subcortex_vi...
- Reposted by Jeremy ElmanThe devastation I feel about this attack on science in particular is hard to cope with. It’s like watching my dad die all over again. I would do anything to spare someone a death via pancreatic cancer.
- A tiny trial in New York has shown that personalized mRNA vaccines can provoke massive, lasting immune responses against pancreatic cancer, even as sweeping federal cuts now threaten the fragile labs required to produce them. theintellectualistofficial.substack.com/p/a-breakthr...
- Reposted by Jeremy ElmanGot with the times + made a BSky to share our new, large-scale spatial RNAseq study of adult human #locuscoeruleus! Co-1st auth and cryostat wizard @heenadivecha.bsky.social squeezed 85 tissue sections into 43 Visium arrays. (1/8) www.biorxiv.org/content/10.1...
- Reposted by Jeremy ElmanPostdoc position: our team is looking for a postdoctoral colleague interested in developing and testing theories of brainstem function in AD using fMRI/PET. The Martinos Center / MGH in Boston is a superb place to work. Reach out if you have any questions. Come and join us! 🎉🔵
- Seriously, thank you to all involved. Study sections and grant reviews are a ton of work in normal times, so the extra effort that is going into this round is MUCH appreciated.
- This world series should have come with a health warning.
- Reposted by Jeremy ElmanHAPPENING NOW: A MASSIVE crowd of protesters flood the streets of San Diego for a “No Kings Day” rally showing their love for America and standing up against the corrupt fascist Trump administration. look how huge it is
- Check out our data! Please reach out if you're interested, we're happy to provide more info and we may have useful datasets (e.g., with extra cleaning or composite variables) to address specific questions. Raw and derived MRI data also available upon request for ~1/2 the cohort.
- 🚨NEW DATA RELEASE🚨 Data from VETSA waves 1-3 is now available for public download from NACDA! This includes cognitive, health, psychosocial and demographic info from our nationwide twin cohort. Future releases will include wave 4 data and derived MRI variables. www.icpsr.umich.edu/web/ICPSR/st...
- Reposted by Jeremy ElmanNew paper out from the lab, demonstrating a robust non-linear relationship between age at menopause and dementia risk. Fantastic work by post-doc Dr. Ursula Saelzler. alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
- Reposted by Jeremy ElmanExcited to share my new study with the VETSA team (vetsa.bsky.social) with jaelman.bsky.social and matthewpanizzon.bsky.social published in #JINS showing that moderate-to-severe chronic pain and opioid use are independently related to risk of mild cognitive impairment. tinyurl.com/y88k5z4j
- Reposted by Jeremy ElmanExcited to share my new K01 work to understand chronic pain as an AD risk factor - a collaboration of the VETSA team (vetsa.bsky.social) with jaelman.bsky.social and matthewpanizzon.bsky.social and Rush Medical University using the ROSMAP data. academic.oup.com/braincomms/a...
- Reposted by Jeremy ElmanStudy from Nathan Gillespie testing causal associations of plasma amyloid on total tau using #VETSA twin data. www.sciencedirect.com/science/arti...
- Reposted by Jeremy ElmanStudy by Alex Posis finding that TBI is associated with altered microstructure of certain WM tracts that may persist at least 4 decades after the injury. www.sciencedirect.com/science/arti...
- Reposted by Jeremy ElmanHappy to share a new published study link.springer.com/article/10.1... on subjective memory concern, negative affect, and cortical microstructure using @vetsa.bsky.social dataset and supported by a K01 grant from the NIA!
- Reposted by Jeremy Elman‼️NEW PREPRINT‼️ What if you could take a normal 3T T1w MRI and make it look like it was acquired from a 7T scanner? That's exactly what we do using AI in our new preprint! Link: arxiv.org/abs/2507.13782 #neuroskyence #neurosky #compneuro #AI #datascience #neurology #mrisky #neuroimaging
- Reposted by Jeremy ElmanIncredibly excited for this new work from our lab. We test the potential of AI-based neurodegenerative disease diagnostics using plasma proteomics data from n>17,000 people, led by the brilliant and indefatigable @anlijuncn.bsky.social Check it out!👇
- Trying to create directory tree for a new project or storage location? I did, but couldn't find an app that did exactly what I wanted, so I had GitHub Copilot + Claude create an app for me. Link to the web app: jelman.github.io/TreeForge/
- With TreeForge you can: 1. Drag and drop folders/files in a visual editor 2. Toggle between markdown (for easier editing) and ASCII (for better visualization) in a text editor 3. Edits sync across windows 3. Import/export JSON and ASCII files to send to others and for data documentation.
- Big caveat: Although it does what I need it to, this is essentially 100% AI created so YMMV. Github repo below if you'd like to modify or build a local app. Hope it's useful! github.com/jelman/TreeF...
- The onslaught of 2025 can be so isolating. Today was a really great reminder that we're a community, and a large one at that.
- San Diego #NoKings
- Reposted by Jeremy ElmanNew work from our postdoc Seraphina Solders shows patterns of blood-brain barrier leakage in cognitively normal APOE4 carriers. BBB breakdown correlated with microstructural brain injury only in groups with high Alzheimer's disease risk (APOE4+, amyloid+, women) www.sciencedirect.com/science/arti...
- This is a popular neighborhood restaurant on a corner with a lot of foot traffic. Rolling in like this on a Friday evening could only have been meant to send a message. It was guaranteed to be packed with folks from the neighborhood, including kids. No wonder they cover their faces.
- Reposted by Jeremy ElmanThank you @60minutes.bsky.social for giving the NIH freezes, termination, and proposed budget cuts the attention they deserve. ALL Americans, regardless of party, will feel this impact to their health far beyond one administration. www.cbsnews.com/video/nih-cu...
- Reposted by Jeremy ElmanThis Passover I’m thinking hard about the holiday’s history of resistance to tyrannical leaders, and the imperative for Jewish people to stand with all oppressed peoples of the world.
- Reposted by Jeremy ElmanNEW: The Trump administration is exploiting a loophole to keep funding frozen at the NIH - a move that some legal scholars say is illegal. Federal Register notices are blocked, so no grant-review sessions can be scheduled. All the gritty details here, and a short 🧵: www.nature.com/articles/d41...
- Reposted by Jeremy ElmanThis account is for sharing info with US scientists, both extramural and intramural to NIH, about attacks on science in the US. Education is power, and we can help advocate for science and medicine together. 💪🧪 We are a team of NIH people. Please ask us questions you might have.
- *Posted for McKenna Williams, not yet on BlueSky* Our new paper on cognitive resilience against Alzheimer’s pathology is out now! onlinelibrary.wiley.com/doi/full/10....
- We explore common conceptual issues (i.e., differentiating resilience vs. low risk) and identify cortical regions that confer resilience against p-tau/cortical thinning 🧠
- Special shout-out to Table 2 which reflects our discussions on model specification and ways to rule out alternate explanations related to cognitive resilience.
- Reposted by Jeremy ElmanThis has a twist. I promise it’s worth it
- Reposted by Jeremy Elman🚨RED ALERT for 🧪: The Trump NIH just gashed indirect costs. This is a direct attack on universities. “Pursuant to this Supplemental Guidance, there will be a standard rate of 15% across all NIH grants for indirect costs.” 😮 Just a devastating Friday night news dump. #scicomm #academicaky
- Reposted by Jeremy ElmanJust in case you thought that removing DEI criteria would mean that everyone is competing equally: NIH is removing grad students from underrepresented backgrounds from the applicant pool altogether. Their applications will not be considered. Other students, not from these backgrounds, will be.
- Reposted by Jeremy Elman🚨BREAKING. From a program officer at the National Science Foundation, a list of keywords that can cause a grant to be pulled. I will be sharing screenshots of these keywords along with a decision tree. Please share widely. This is a crisis for academic freedom & science.
- Reposted by Jeremy ElmanNEW: Trump says he's letting "lifesaving" foreign aid continue, but sources tell WIRED that DOGE is still blocking HIV/AIDS relief. Musk brags he's "feeding USAID into the wood chipper." A USAID worker tell us: “At a minimum, 300 babies that wouldn’t have had HIV now do." By @knibbs.bsky.social
- Happy to see this paper led by Caroline McGrouther and Adi Rangan published. Biclustering was used to identify a genetic subtype of bipolar disorder. Accounting for heterogeneity by leveraging bicluster information reduced noise in GWAS and improved risk prediction. journals.plos.org/plosone/arti...
- Reposted by Jeremy ElmanI hope you will all join me in expressing your thanks to the NIH and NSF staff who are working in an impossibly difficult and chaotic environment to keep science going in our country.
- It's a very scary and confusing time right now. I know many of you have already been affected, either directly or indirectly. I'm still unsure what to do next, but felt like it was important to at least acknowledge that things are, in fact, bad.
- Reposted by Jeremy ElmanWithout congressional approval or constitutional authority, the richest man in the world has taken over payroll of the US government. How is this not a coup?
- Reposted by Jeremy ElmanThe entire website for the NIH Office of Research on Women's Health (ORWH) is very nearly stripped bare. This is so, so devastating. orwh.od.nih.gov/research/fun...
- Was just reading through a thread and thinking to myself, "wow, bluesky sure has gotten scary quickly." Then I realized I had accidentally opened Twitter. Yikes, that place is a cesspool! Makes me appreciate this place even more.
- Reposted by Jeremy ElmanI think some people hear “grants” and think that without them, scientists and government workers just have less stuff to play with at work. But grants fund salaries for students, academics, researchers, and people who work in all areas of public service. “Pausing” grants means people don’t eat.
- Reposted by Jeremy Elmanwhat would you do differently if you were trying to legalize discrimination?
- Please RT or pass along to anyone looking for postdoc positions! Ample opportunity to pursue new and existing interests and gain training across multiple areas. This will include causal modeling of potentially modifiable risk factors of AD.
- Reposted by Jeremy Elman"A study of federally funded research projects in the United States estimated that principal investigators spend on average about 45% of their time on administrative activities related to applying for and managing projects rather than conducting active research" www.pnas.org/doi/10.1073/...
- Very nice paper by @rongxiang.bsky.social looking at lifecourse impacts of childhood disadvantage on brain structure and cognition.
- New article led by @rongxiang.bsky.social examining the effects of childhood disadvantage on late midlife cortical surface area (SA) profile and general cognitive ability (GCA). Cortical SA was found to be the mediator of childhood disadvantage-GCA association. academic.oup.com/psychsocgero...
- New article describing a regional parcellation scheme of abnormal white matter developed using #VETSA data!
- New article led by @cfnote.bsky.social and Shu-Ju Lin describing a novel parcellation of abnormal white matter w/ 5 distinct regions. Twin models identified common & unique genetic and environmental influences that may reflect variable underlying etiologies. onlinelibrary.wiley.com/doi/10.1002/...
- Reposted by Jeremy ElmanFor those going home to visit family this weekend: • Samsung calls it Auto Motion Plus • LG calls it TruMotion • Sony calls it Motionflow • Roku calls it Action Smoothing • Google TV calls it Motion Enhancement • Vizio calls it Smooth Motion Effect.
- Reposted by Jeremy ElmanI'm compiling a list of researchers whose work relates to cognitive and computational neurology for Alzheimer's and related dementia. Must have missed many, so let me know if you feel you should be added! go.bsky.app/VcJLzRzat://did:plc:mu2gskmbtqojxaqcsqdd4uyp/app.bsky.graph.starterpack/3lbpeyytuxi2t
- Reposted by Jeremy Elman[This post could not be retrieved]
