Nature Reviews Endocrinology

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  Nature Reviews Endocrinology natrevendo.nature.com · 21h
  ICYMI: New content online: Brain neurons promote skeletal dysfunction in ageing
  

  Brain neurons promote skeletal dysfunction in ageing

  Nature Reviews Endocrinology, Published online: 03 February 2026; doi:10.1038/s41574-026-01233-0Brain neurons promote skeletal dysfunction in ageing

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  Nature Reviews Endocrinology natrevendo.nature.com · 21h
  ICYMI: New content online: Blood–brain barrier permeability of adipokines and myokines

  Blood–brain barrier permeability of adipokines and myokines

  Nature Reviews Endocrinology, Published online: 03 February 2026; doi:10.1038/s41574-026-01232-1The use of adipokines and myokines measured in serum or cerebrospinal fluid as biomarkers or disease modifiers in neurological disorders is limited. Their permeability to the blood–brain barrier is either unknown or overlooked. A novel classification of adipokines and myokines on the basis of their cerebrospinal fluid to serum ratio is warranted.

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  Nature Reviews Endocrinology natrevendo.nature.com · Feb 4
  New content online: Brain neurons promote skeletal dysfunction in ageing
  

  Brain neurons promote skeletal dysfunction in ageing

  Nature Reviews Endocrinology, Published online: 03 February 2026; doi:10.1038/s41574-026-01233-0Brain neurons promote skeletal dysfunction in ageing

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  Nature Reviews Endocrinology natrevendo.nature.com · Feb 4
  This Research Highlight discusses a paper published in @nataging.nature.com - www.nature.com/articles/s43...
  

  Brain neuron-derived WDFY1 induces bone loss - Nature Aging

  Chen et al. identify a brain-to-bone communication axis whereby extracellular vesicles from aged brain neurons transport WDFY1 protein to distal bone, driving bone-fat imbalance and promoting osteopor...

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  Nature Reviews Endocrinology natrevendo.nature.com · Feb 4
  New content online: Blood–brain barrier permeability of adipokines and myokines

  Blood–brain barrier permeability of adipokines and myokines

  Nature Reviews Endocrinology, Published online: 03 February 2026; doi:10.1038/s41574-026-01232-1The use of adipokines and myokines measured in serum or cerebrospinal fluid as biomarkers or disease modifiers in neurological disorders is limited. Their permeability to the blood–brain barrier is either unknown or overlooked. A novel classification of adipokines and myokines on the basis of their cerebrospinal fluid to serum ratio is warranted.

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