Annabelle Singer
Neuroscientist & Neuroengineer at Georgia Tech and Emory. Learning, memory, and memory impairment in disease, oh my.
- "...Add soccer practice and music lessons and doctors’ appointments, and so begins a tormented dance of the privileged, to-ing and fro-ing through rush hour as any zest for life disintegrates." This one sentence eloquently tells the story of a daily parenting struggle www.nytimes.com/2026/01/05/u...
- Check out this podcast highlighting our research and BME research more broadly. Thanks @danzigerzachary.bsky.social and Erin Buckley for making this happen
- Reposted by Annabelle SingerGarrett Stanley and I are leading the recruitment of a senior faculty position in BME at Georgia Tech and Emory, focused on Neural Engineering. Come talk to us, we're looking for a leader in research and training, in areas with neurotranslation potential. More details here: lnkd.in/eusCqCSR
- Reposted by Annabelle SingerSubmissions for late-breaking abstracts are now open! Share your most recent and exciting research with a global audience at #SfN25. Submit your late-breaking abstract by Wednesday, September 10. 🔗 vist.ly/45gzc #neurosky #neuroskyence #academicchatter
- Check out new findings from @TinaFranklin: "Sensory neurostimulation promotes stress resilience with frequency-specificity" on bioRxiv: www.biorxiv.org/content/10.1... Chronic stress is a major risk factor for neuropsychiatric and neurodegenerative diseases, but for many of us it's unavoidable.
- Can we experience stress without the damaging effects? Here, we find that non-invasive sensory stimulation at the right frequency induces stress resilience. Tina started this project with a creative idea: can we use sensory stimulation to prevent the damaging effects of chronic stress?
- Tina’s insight was based putting together separate fields showing, on the one hand that chronic stress causes damage via maladaptive neuroimmune responses and on the other hand that sensory stimulation alters neuroimmune function in unstressed conditions.
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View full threadand was made possible by collaborations with the labs of Levi Wood and @sloanlab.bsky.social Preprint is here: www.biorxiv.org/content/10.1...
- Reposted by Annabelle Singer#SfN25 provides an unparalleled scientific program highlighting emerging science from across the field. Get a first look at speakers, events, lectures, and more in the Neuroscience 2025 Preliminary Program. 🔗 vist.ly/3xvcw Drop a comment below to let us know your big three! #neurosky
- Check out new work by Sara Bitarafan showing that the frequency and duration of audiovisual flicker stimulation are key variables that dictate how flicker affects immune, neuronal, and metabolic genes in the context of Alzheimer’s disease pathology: doi.org/10.1063/5.02....
- These insights enable stimulation “tuning” to target specific functions. This work also highlights how flicker stimulation has multiple biological effects and we think such a multipotent therapeutic approach is required for neurodegenerative diseases. This study was made possible by Levi Wood’s lab
- and by funding from the CART foundation, the NIH, the NSF, the BrightFocus foundation, and the Alzheimer’s Association. The paper is here: doi.org/10.1063/5.02...
- @stephmprince.bsky.social's recent paper was included in the Editors’ page “From brain to behaviour”. Check it out here: www.nature.com/collections/... Editors’ Highlights pages showcase exciting recent papers in an area.
- Joshua Stewart explains our recent paper by @stephmprince.bsky.social on how our brains adapt in a dynamic environment to still reach our destination: coe.gatech.edu/news/2025/06... This work was supported by the NIH, NSF, McCamish Foundation, and Packard Foundation
- The paper is here: www.nature.com/articles/s41...
- SFN abstracts are due Wednesday, June 4, at 5 p.m. Eastern Daylight Time.
- Groundbreaking scientific discoveries don’t happen in isolation. Michelle Gray, PhD, SfN Program Committee member, shares how you can enhance your research through valuable exchange w/ the global scientific community at #SfN25. Don't delay, submit your abstract today! 🔗 bit.ly/3G5vEde #NeuroSky
- We live in a dynamic world, but we often study navigation as if the world is static. So how do we flexibly adapt in the face of new, pivotal information? @stephmprince.bsky.social addresses just that question in her latest paper: www.nature.com/articles/s41....
- To do this, Steph developed a new behavioral paradigm in which we leverage a dynamic, virtual-reality environment to precisely control the introduction of new information while animal’s choices are evolving in a memory-based decision-making task.
- In hippocampus, we found that new, pivotal information causes non-local representations of both possible goal locations to rapidly increase, simulating both possible outcomes. In prefrontal cortex we found that pivotal information causes choice codes to rapidly switch to represent the new choice.
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View full threadSteph pioneered this new take on prospective codes including this complex behavior. The paper would not have been possible without the help of Danielle Cushing. Link for the smart PDF: rdcu.be/enokS
- Reposted by Annabelle SingerExcited to share the last project from my PhD is officially published: www.nature.com/articles/s41...!
- Reposted by Annabelle Singer📣 #SfN25 abstract submission is now open! Share your research with the global neuroscience community. Start now to avoid the last-minute rush! 🔗 bit.ly/3G5vEde #NeuroSky #AcademicChatter
- A major milestone for biomedical science and people with uncommon genetic disease: "KJ’s treatment — which built on decades of federally funded research — offers a new path for companies to develop personalized treatments" www.nytimes.com/2025/05/15/h...
- Our research, funded by the NIH, was just featured on FOX 5! Thanks to interviewer Kevyn Stewart for sharing how Nuri Jeong's grandmother inspired her research, recently published in @nature.com. Get a glimpse into the lab here: www.fox5atlanta.com/news/georgia...
- Thanks you NIA for making this work possible
- Reposted by Annabelle SingerWrote a review with some thoughts about dopamine's role in movement. Hope people find it useful and/or stimulating! Thanks again to @bensaunders.bsky.social for the invitation and editing this issue. kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F...
- Check out our new paper out today in PNAS: “40 Hz sensory stimulation enhances CA3-CA1 coordination and prospective coding during navigation in a mouse model of Alzheimer’s disease”. www.pnas.org/doi/10.1073/... Led by Abigail Paulson with Lu Zhang and Ashley Prichard @amprichard.bsky.social
- Despite recent work on how 40 Hz sensory stimulation, or “flicker” affects disease models and human patients, it’s unknown how flicker impacts neural correlates of memory.
- Using recordings of 1000s of neurons during virtual reality navigation behavior and Bayesian decoding, Abby discovered that 40 Hz flicker enhances representations of future positions, or prospective coding. These representations of future position coincide with efficient and engaged navigation.
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View full threadThis study reveals that chronic 40 Hz flicker enhances hippocampal activity that is essential for memory. This work also demonstrates a new way to evaluate brain stimulation for Alzheimer’s disease, by assessing its effects on memory processes. Full paper is here: www.pnas.org/doi/10.1073/...
- Reposted by Annabelle SingerInspired by Georgia Tech researchers' personal experiences with Alzheimer's, a recent study published in @nature.com shows how inhibition isn't just about stopping activity but precisely timing it to enhance learning. neuro.gatech.edu/when-less-mo...
- Check out this story by Jerry Grillo @fourcrickets.bsky.social about our recent paper: bme.gatech.edu/bme/news/whe... @gatechengineers.bsky.social @gt-neuro.bsky.social @gtresearchnews.bsky.social
- Check out this story by Jerry Grillo @fourcrickets.bsky.social about our recent paper: bme.gatech.edu/bme/news/whe... @gatechengineers.bsky.social @gt-neuro.bsky.social @gtresearchnews.bsky.social
- The scientific paper is here: www.nature.com/articles/s41...
- Check out our latest paper today in Nature: “Goal specific hippocampal inhibition gates learning” www.nature.com/articles/s41... By Nuri Jeong, Xiao Zheng, Abby Paulson, Steph Prince and colleagues.
- Navigating the world depends on rapidly learning the paths to important places. This process has long been attributed to the activity of excitatory neurons that represent places while inhibitory interneurons were thought to play only supporting roles.
- Nuri and Xiao found that inhibitory interneurons are central to swiftly learning important places. We discovered that interneurons act as gatekeepers that open specifically on paths to important locations and enable learning for those places.
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View full threadArt with the first post is “Gateway to Memory” by Myriam Wares.
