CortesMalaria Lab
Scientists passionate about understanding #epigenetic and #transcriptional processes in #malaria #parasites. We also like #gametocytes!
cortesmalarialab.wordpress.com
- It’s beginning to look a lot like Christmas! 🎵 Merry Christmas and happy holidays to everyone! 🎄🎁🍾 The Epis send you warm holiday wishes from our brand-new lab location @www.pcb.ub.edu ✨✨✨
- Curious about which thermal 🌡️and non-thermal 💊conditions activate the AP2-HS-dependent heat-shock response in Plasmodium falciparum? Check out our new preprint in Biorxiv!📊🧪 www.biorxiv.org/content/10.1...
- 📣Rush to read our latest paper!! journals.plos.org/plospathogen.... You'll learn why #heterochromatin is formed and maintained in specific regions of the Plasmodium falciparum genome and not others 🧵⬇️
- 💡We found that DNA sequences of genes such as ap2-g or var are sufficient to trigger heterochromatin formation when integrated in an euchromatic locus 😯
- Heterochromatin formation is very efficient at var upstream sequences, but it is inefficient for ap2-g 5'CDS sequences, which require looooong DNA sequences and only occurs in a few parasites. Other sequences tested cannot nucleate heterochromatin formation at all! 🤪
- 🧬We also show that maintenance of heterochromatin at the ap2-g locus depends on the sequences from the putative ap2-g promoter. ▶️Go ahead and take a look! You'll find more juicy details in the paper!! 🤗
- Our colleagues and us have been abducted from the lab!!! 🆘👽 If you see these ISGlobaliens around Barcelona, don't be shy and ask for a ride in their fantastic UFO! 🤩🛸
- 📣📣See our new preprint in Biorxiv, in which we explore the role of the primary DNA sequence 🧬 in de novo heterochromatin formation and maintenance 🔍📊🧩 www.biorxiv.org/content/10.1...
- Welcome to our new Bluesky account!!👋😊Lots of science and fun ahead! 🔬🧪🥼🤩
